Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Pro-inflammatory immune system development, metabolomic defects, and deregulation of
autophagy play interconnected roles in driving the pathogenesis of systemic lupus …

NGAL holds promise as a versatile biomarker in SLE whereas urine ALCAM, CD163 and
VCAM-1 displayed good performance as biomarkers in LN. The overall lack of concerted …

Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with
multiorgan inflammatory involvement and a mortality rate that is 2.6-fold higher than …

Lupus nephritis (LN) is one of the most severe complications in patients with systemic lupus
erythematosus (SLE). Traditionally, LN is regarded as an immune complex (IC) deposition …

Introduction Systemic lupus erythematosus (SLE) is complex autoimmune disease with
heterogenous manifestations, unpredictable disease course and response to treatment. One …

Lupus nephritis (LN) is the main manifestation of systemic Lupus Erythematosus (SLE).
MicroRNAs (miRNAs) and autoantibodies could be suitable candidate biomarkers of LN …

Despite conventional therapy, lupus nephritis (LN) remains a significant contributor to short-
and long-term morbidity and mortality. B cell abnormalities and the production of …

Introduction Complement system overactivation is pivotal in lupus nephritis (LN)
pathophysiology. Considering that anti-C3 autoantibodies play a significant role in LN …

Background Autoantibody biomarkers are valuable tools used to diagnose and manage
autoimmune diseases in dogs. However, prior publications have raised concerns over a lack …