Arterial stiffness as a risk factor for clinical hypertension

ME Safar - Nature Reviews Cardiology, 2018 - nature.com
In patients with uncomplicated essential hypertension, cardiac output remains within normal
ranges and intravascular volume is normal or low, assuming the presence of a sufficient …

[HTML][HTML] Aortic stiffness: epidemiology, risk factors, and relevant biomarkers

R Angoff, RC Mosarla, CW Tsao - Frontiers in cardiovascular …, 2021 - frontiersin.org
Aortic stiffness (AoS) is a maladaptive response to hemodynamic stress and both modifiable
and non-modifiable risk factors, and elevated AoS increases afterload for the heart. AoS is a …

[HTML][HTML] The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus

DZI Cherney, BA Perkins, N Soleymanlou… - Cardiovascular …, 2014 - Springer
Background Individuals with type 1 diabetes mellitus are at high risk for the development of
hypertension, contributing to cardiovascular complications. Hyperglycaemia-mediated …

[HTML][HTML] Pooled analysis of Phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozin

DZI Cherney, ME Cooper, I Tikkanen, E Pfarr… - Kidney international, 2018 - Elsevier
Sodium glucose cotransporter 2 (SGLT2) inhibitors reduce HbA1c, blood pressure, and
weight in patients with type 2 diabetes. To investigate the effect of renal function on …

[HTML][HTML] Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus

PM Carlucci, MM Purmalek, AK Dey… - JCI insight, 2018 - ncbi.nlm.nih.gov
BACKGROUND. Systemic lupus erythematosus (SLE) is associated with enhanced risk of
atherosclerotic cardiovascular disease not explained by Framingham risk score (FRS) …

Cardio-ankle vascular index is independently associated with future cardiovascular events in outpatients with metabolic disorders

Y Sato, D Nagayama, A Saiki, R Watanabe… - … of atherosclerosis and …, 2016 - jstage.jst.go.jp
Aim: We investigated whether cardio-ankle vascular index (CAVI), an arterial stiffness
marker, independently predicts future cardiovascular events in subjects with metabolic …

Hypertension, diabetes type II, and their association: role of arterial stiffness

H Smulyan, A Lieber, ME Safar - American journal of …, 2016 - academic.oup.com
In patients with both hypertension and type II diabetes, the systolic blood pressure (SBP)
increases linearly with age, while that of diastolic blood pressure (DBP) declines …

Indirect measure of visceral adiposity 'A Body Shape Index'(ABSI) is associated with arterial stiffness in patients with type 2 diabetes

R Bouchi, M Asakawa, N Ohara, Y Nakano… - BMJ Open Diabetes …, 2016 - drc.bmj.com
Objective Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which
is defined as waist circumference (WC)/(body mass index (BMI) 2/3× height1/2), is unique in …

Aortic stiffness: pathophysiology, clinical implications, and approach to treatment

S Sethi, O Rivera, R Oliveros… - Integrated blood pressure …, 2014 - Taylor & Francis
Aortic stiffness is a hallmark of aging, and classic cardiovascular risk factors play a role in
accelerating this process. Current changes in medicine, which focus on preventive care …

Prognostic value of arterial stiffness measurements in cardiovascular disease, diabetes, and its complications: The potential role of sodium‐glucose co‐transporter‐2 …

D Patoulias, C Papadopoulos… - The Journal of …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) constitutes a global pandemic, representing the 7th cause
of death worldwide. Morbidity and mortality of patients with T2DM are gradually increasing …