Vitamin B 6 is one of the most central molecules in cells of living organisms. It is a critical co-
factor for a diverse range of biochemical reactions that regulate basic cellular metabolism …

For the past 20 years, the Clusters of Orthologous Genes (COG) database had been a
popular tool for microbial genome annotation and comparative genomics. Initially created for …

Pyridoxal 5′-phosphate (PLP), the active form of vitamin B 6, functions as a cofactor in
humans for more than 140 enzymes, many of which are involved in neurotransmitter …

Global warming is a major abiotic stress factor, which limit rice production. Exploiting the
genetic basis of the natural variation in heat resistance at different reproductive stages …

SUMMARY B vitamins are a group of water‐soluble micronutrients that are required in all life
forms. With the lack of biosynthetic pathways, humans depend on dietary uptake of these …

Biallelic pathogenic variants in PLPBP (formerly called PROSC) have recently been shown
to cause a novel form of vitamin B6-dependent epilepsy, the pathophysiological basis of …

Vitamin B6 is a designation for the six vitamers pyridoxal, pyridoxine, pyridoxamine,
pyridoxal 5′-phosphate (PLP), pyridoxine 5′-phosphate, and pyridoxamine. PLP, being …

The cyanobacterial protein PipY belongs to the Pyridoxal-phosphate (PLP)-binding proteins
(PLPBP/COG0325) family of pyridoxal-phosphate-binding proteins, which are represented …

PII, a homotrimeric very ancient and highly widespread (bacteria, archaea, plants) key
sensor-transducer protein, conveys signals of abundance or poorness of carbon, energy …

Vitamin B6 is an ensemble of six interconvertible vitamers: pyridoxine (PN), pyridoxamine
(PM), pyridoxal (PL), and their 5′-phosphate derivatives, PNP, PMP, and PLP. Pyridoxal …