Inflammation is favorable in most cases, because it is a kind of body defensive response to
external stimuli; sometimes, inflammation is also harmful, such as attacks on the body's own …

Lipoxygenases (LOXs) catalyze the (per) oxidation of fatty acids that serve as important
mediators for cell signaling and inflammation. These reactions are initiated by a CH …

Human 15-lipoxygenase-1 (h-15-LOX-1) is a mammalian lipoxygenase and plays an
important role in several inflammatory lung diseases such as asthma, COPD, and chronic …

Abstract The enzyme 15-lipoxygenase-1 (15-LOX-1) plays a dual role in diseases with an
inflammatory component. On one hand 15-LOX-1 plays a role in pro-inflammatory gene …

Various mechanisms for regulated cell death include the formation of oxidative mediators
such as lipid peroxides and nitric oxide (NO). In this respect, 15-lipoxygenase-1 (15-LOX-1) …

Chalcones represent a class of small drug/druglike molecules with different and multitarget
biological activities. Small multi-target drugs have attracted considerable interest in the last …

Abstract Cytochrome P450 2J2 (CYP2J2) is overexpressed in human carcinoma cells lines
and malignant tumors, and has been closely related to the pathogenesis of cancers and …

We report the synthesis of a macrocyclic Gd chelate based on a 1, 4, 7, 10-
tetraazacyclododecane-1, 4, 7-trisacetic acid (DO3A) coordinationn cage bearing an …

Abstract Human 15-lipoxygenase-1 (15-LOX-1) is a mammalian lipoxygenase which plays
an important regulatory role in several CNS and inflammatory lung diseases. To further …

A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum
symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone …