The pilocarpine model of mesial temporal lobe epilepsy: Over one decade later, with more rodent species and new investigative approaches

M Lévesque, G Biagini, M de Curtis… - Neuroscience & …, 2021 - Elsevier
Fundamental work on the mechanisms leading to focal epileptic discharges in mesial
temporal lobe epilepsy (MTLE) often rests on the use of rodent models in which an initial …

[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Effects of single cage housing on stress, cognitive, and seizure parameters in the rat and mouse pilocarpine models of epilepsy

H Manouze, A Ghestem, V Poillerat, M Bennis… - Eneuro, 2019 - eneuro.org
Many experimental approaches require housing rodents in individual cages, including in
epilepsy research. However, rats and mice are social animals; and individual housing …

Brain pathology in focal status epilepticus: evidence from experimental models

M de Curtis, AO Rossetti, DV Verde, EA van Vliet… - Neuroscience & …, 2021 - Elsevier
Status Epilepticus (SE) is often a neurological emergency characterized by abnormally
sustained, longer than habitual seizures. The new ILAE classification reports that SE “… can …

Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored …

AS Galanopoulou, W Löscher, L Lubbers… - Epilepsia …, 2021 - Wiley Online Library
Epilepsy is one of the most common chronic brain diseases and is often associated with
cognitive, behavioral, or other medical conditions. The need for therapies that would …

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models …

AM Katsarou, H Kubova, S Auvin… - Epilepsia …, 2022 - Wiley Online Library
Epilepsy syndromes during the early years of life may be attributed to an acquired insult,
such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These …

A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3‐WG1B: Paediatric and genetic models working group …

M Mantegazza, S Auvin, M Barker‐Haliski… - Epilepsia …, 2022 - Wiley Online Library
Rodent models of epilepsy remain the cornerstone of research into the mechanisms
underlying genetic epilepsy. Reproducibility of experiments using these rodent models …

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4 …

L Bindila, T Eid, JD Mills, MS Hildebrand… - Epilepsia …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES)
Joint Translational Task Force established the TASK3 working groups to create common …

A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3‐WG4 …

EA van Vliet, MS Hildebrand, JD Mills… - Epilepsia …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES)
Joint Translational Task Force established the TASK3 working groups to create common …

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 …

E Aronica, DK Binder, M Drexel, C Ikonomidou… - Epilepsia …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES)
Joint Translational Task Force initiated the TASK3 working group to create common data …