Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …

Cadmium is a non-essential element that has high rates of soil to plant transference
compared with other non-essential elements, and certain plant species accumulate large …

Recent studies have indicated that arachidonic acid is primarily metabolized by cytochrome
P-450 (CYP) enzymes in the brain, lung, kidney, and peripheral vasculature to 20 …

Gender has an important influence on blood pressure, with premenopausal women having a
lower arterial blood pressure than age-matched men. Compared with premenopausal …

The protease renin is the key enzyme of the renin-angiotensin-aldosterone cascade, which
is relevant under both physiological and pathophysiological settings. The kidney is the only …

Fatty acids (FAs) can be degraded via different mechanisms including α‐, β‐and ω‐
oxidation. In humans, a range of different genetic diseases has been identified in which …

Since the initial reports that renal cytochrome P450 (CYP) enzymes can metabolize
arachidonic acid to substances which affect arterial tone, it has become increasingly clear …

Cardiovascular diseases (CVDs) remain the leading cause of death in the developed
countries. Taking into account the mounting evidence about the role of cytochrome P450 …

Abstract Cytochrome P450s (P450) metabolize arachidonic acid (AA) to
hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs). Among these …