Present status of microfluidic PCR chip in nucleic acid detection and future perspective

S Chen, Y Sun, F Fan, S Chen, Y Zhang… - TrAC Trends in …, 2022 - Elsevier
Polymerase chain reaction (PCR) amplifies specific fragment of DNA molecules and has
been extensively applied in fields of pathogens and gene mutation detection, food safety …

Aptamer-based biosensors and nanosensors for the detection of vascular endothelial growth factor (VEGF): A review

S Dehghani, R Nosrati, M Yousefi, A Nezami… - Biosensors and …, 2018 - Elsevier
Vascular endothelial growth factor (VEGF) is a key regulator of vascular formation and a
predominant protein biomarker in cancer angiogenesis. Owing to its crucial roles in the …

Point-of-care-testing of nucleic acids by microfluidics

L Zhang, B Ding, Q Chen, Q Feng, L Lin… - TrAC Trends in Analytical …, 2017 - Elsevier
Nucleic acid detection offers critical information in diagnosing pathogen infection and
monitoring disease treatment. Point-of-care testing (POCT), with ideal characteristics such …

Lab-on-a-chip systems for aptamer-based biosensing

NI Khan, E Song - Micromachines, 2020 - mdpi.com
Aptamers are oligonucleotides or peptides that are selected from a pool of random
sequences that exhibit high affinity toward a specific biomolecular species of interest …

A novel M-shape electrochemical aptasensor for ultrasensitive detection of tetracyclines

SM Taghdisi, NM Danesh, M Ramezani… - Biosensors and …, 2016 - Elsevier
Analytical techniques for detection and quantitation of tetracyclines in food products are
greatly in demand. In this study, a novel electrochemical aptasensor was designed for …

Recent advances on G-quadruplex for biosensing, bioimaging and cancer therapy

J Xu, R Jiang, H He, C Ma, Z Tang - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
G-quadruplex is a three-dimensional secondary structure of nucleic acids formed by the
Hoogsteen hydrogen pairing of four guanines. Diverse topologies of G-quadruplex could be …

Automation and miniaturization: enabling tools for fast, high‐throughput process development in integrated continuous biomanufacturing

TC Silva, M Eppink, M Ottens - Journal of Chemical …, 2022 - Wiley Online Library
Process development in the biotech industry leads to investments around hundred of
millions of dollars. It is important to mitigate costs without neglecting the quality of process …

Microfluidics-based sensing of biospecies

Y Xing, L Zhao, Z Cheng, C Lv, F Yu… - ACS Applied Bio …, 2020 - ACS Publications
Over the past decades, microfluidic devices based on many advanced techniques have
aroused widespread attention in the fields of chemical, biological, and analytical …

A highly sensitive VEGF165 photoelectrochemical biosensor fabricated by assembly of aptamer bridged DNA networks

H Da, H Liu, Y Zheng, R Yuan, Y Chai - Biosensors and Bioelectronics, 2018 - Elsevier
We developed a novel “signal-off” photoelectrochemical (PEC) aptasensor based on an
aptamer bridged DNA network structure for the sensitive detection of vascular endothelial …

An electrochemiluminescence cloth-based biosensor with smartphone-based imaging for detection of lactate in saliva

Y Yao, H Li, D Wang, C Liu, C Zhang - Analyst, 2017 - pubs.rsc.org
Cloth fabrics and smartphones have become the two things people are most familiar with.
Particularly, smartphones are used as portable personal computers, revolutionizing …