Coronary artery bypass graft surgery: the past, present, and future of myocardial revascularisation

M Diodato, EG Chedrawy - Surgery research and practice, 2014 - Wiley Online Library
The development of the heart‐lung machine ushered in the era of modern cardiac surgery.
Coronary artery bypass graft surgery (CABG) remains the most common operation …

Therapeutic applications of DNA and RNA aptamers

KW Thiel, PH Giangrande - Oligonucleotides, 2009 - liebertpub.com
Structured single-stranded nucleic acids, or aptamers, bind target molecules with high
affinity and specificity, which translates into unique therapeutic possibilities. Currently …

Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a …

JH Alexander - JAMA: Journal of the American Medical …, 2005 - search.ebscohost.com
Context Coronary artery bypass graft (CABG) surgery with autologous vein grafting is
commonly performed. Progressive neointimal hyperplasia, however, contributes to …

[HTML][HTML] Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery

RD Lopes, GE Hafley, KB Allen… - … England Journal of …, 2009 - Mass Medical Soc
Background Vein-graft harvesting with the use of endoscopy (endoscopic harvesting) is a
technique that is widely used to reduce postoperative wound complications after coronary …

Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery

RD Lopes, RH Mehta, GE Hafley, JB Williams… - Circulation, 2012 - Am Heart Assoc
Background—Vein graft failure (VGF) is common after coronary artery bypass graft surgery,
but its relationship with long-term clinical outcomes is unknown. In this retrospective …

Frequency and predictors of internal mammary artery graft failure and subsequent clinical outcomes: insights from the Project of Ex-vivo Vein Graft Engineering via …

RE Harskamp, JH Alexander, TB Ferguson Jr… - Circulation, 2016 - Am Heart Assoc
Background—The internal mammary artery (IMA) is the preferred conduit for bypassing the
left anterior descending (LAD) artery in patients undergoing coronary artery bypass grafting …

Activation and inflammation of the venous endothelium in vein graft disease

AO Ward, M Caputo, GD Angelini, SJ George, M Zakkar - Atherosclerosis, 2017 - Elsevier
The long saphenous vein is the most commonly used conduit in coronary artery bypass graft
(CABG) surgery when bypassing multiple diseased arteries; however, its use is complicated …

Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial

RE Harskamp, JH Alexander, PJ Schulte… - JAMA …, 2014 - jamanetwork.com
Importance In vitro and animal model data suggest that intraoperative preservation solutions
may influence endothelial function and vein graft failure (VGF) after coronary artery bypass …

Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV

MJ Magee, JH Alexander, G Hafley… - The Annals of thoracic …, 2008 - Elsevier
BACKGROUND: This analysis compares 1-year vein graft patency and major adverse
cardiac and cerebral events (MACCE [death, myocardial infarction, or stroke]) in on-pump …

Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes …

RH Mehta, TB Ferguson, RD Lopes, GE Hafley… - Circulation, 2011 - Am Heart Assoc
Background—Limited information exists on the intermediate-term graft patency and 5-year
clinical outcomes of patients receiving saphenous vein grafts with multiple (m-SVG) versus …