As a severe and highly contagious infectious disease, coronavirus disease 2019 (COVID-
19) has caused a global pandemic. Several case reports have demonstrated that the …

Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can
periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli …

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a
lifelong latent infection in the human host. Following primary replication in mucosal epithelial …

[Frontiers in Bioscience 12, 1615-1628, January 1, 2007] 1615 Corticotropin-releasing hormone
and the blood-brain-barrier Theoha Page 1 [Frontiers in Bioscience 12, 1615-1628, January 1 …

Success of long duration space missions will depend upon robust immunity. Decreased
immunity has been observed in astronauts during short duration missions, as evident by the …

Herpes simplex virus type 1 (HSV-1) as a possible infectious etiology in Alzheimer's disease
(AD) has been proposed since the 1980s. The accumulating research thus far continues to …

Following acute infection, sensory neurons in trigeminal ganglia (TG) are important sites for
the life-long latency of human alpha-herpes virus 1 (HSV-1). Acute or chronic stress in …

Innate immune responses can impact different stages of viral life cycles. Herpes simplex
virus latent infection of neurons and subsequent reactivation provide a unique context for …

Recent studies have shown that cytomegalovirus (CMV) may be an emerging marker of
immunosenescence. CMV can affect the immune system by directly infecting leukocytes and …

Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically
reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully …