The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision.
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

Objectives The liberalisation of cannabis laws, the increasing availability and potency of
cannabis has renewed concern about the risk of psychosis with cannabis. Methods The …

Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Despite widespread evidence of endocannabinoid system involvement in the
pathophysiology of psychiatric disorders, our understanding remains rudimentary. Here we …

Lipids are essential to brain functions, yet they remain largely unexplored. Here we
investigated the lipidome composition of prefrontal cortex gray matter in 396 cognitively …

The prefrontal cortex (PFC) provides executive control of the brain in humans and rodents,
coordinating cognitive, emotional, and behavioral responses to threatening stimuli and …

Mental disorders have a high prevalence compared with many other health conditions and
are the leading cause of disability worldwide. Several studies performed in the last years …

The recent shift in socio-political debates and growing liberalization of Cannabis use across
the globe has raised concern regarding its impact on vulnerable populations such as …

The therapeutic benefits of the current medications for patients with psychiatric disorders
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …