Purpose To synthesize the evidence on the impact on progression-free survival (PFS) and
overall survival (OS) of supramaximal resection (SMR) over gross total resection (GTR) in …

Historically, pathological brain lesions provided the foundation for localization of symptoms
and therapeutic lesions were used as a treatment for brain diseases. New medications …

Background Therapeutic ultrasound (US) has been extensively explored for its inherent high
tissue-penetrating capability and on-demand irradiation without radioactive damage …

Magnetic resonance–guided high-intensity focused ultrasound thalamotomy is a Food and
Drug Administration–approved treatment for essential tremor. The target, the ventral …

Parkinson's disease (PD) is a common neurodegenerative disease, and apart from a few
rare genetic causes, its pathogenesis remains largely unclear. Recent scientific interest has …

MRI-guided high-intensity focused ultrasound thalamotomy is an incisionless therapy for
essential tremor. To reduce adverse effects, the field has migrated to treating at 2 mm above …

Abstract Background Exercise-related signaling Fndc5/irisin expresses in brain and acts as
a crucial regulator of cognitive function, but its detailed roles in vascular dementia (VaD) are …

Background Essential tremor (ET) can be debilitating. Treatments for ET include beta-
blockers and surgical interventions. Low-intensity focused ultrasound (LIFU) may offer an …

OBJECTIVE Tractography-based direct targeting of the ventral intermediate nucleus (T-VIM)
is a novel method that provides patient-specific VIM coordinates. This study aimed to explore …

Cortico-striato-thalamo-cortical (CSTC) loops are fundamental organizing units in
mammalian brains. CSTCs process limbic, associative, and sensorimotor information in …