Epigenetic regulation of microRNAs in cancer: shortening the distance from bench to bedside

MJ Pajares, E Alemany-Cosme, S Goñi… - International Journal of …, 2021 - mdpi.com
Cancer is a complex disease involving alterations of multiple processes, with both genetic
and epigenetic features contributing as core factors to the disease. In recent years, it has …

[HTML][HTML] Impairment of HIF-1α-mediated metabolic adaption by NRF2-silencing in breast cancer cells

S Lee, SP Hallis, KA Jung, D Ryu, MK Kwak - Redox Biology, 2019 - Elsevier
Hypoxia, a common element in the tumor environment, leads to Hypoxia-Inducible Factor-1α
(HIF-1α) stabilization to modulate cellular metabolism as an adaptive response. In a …

MicroRNAs: the link between the metabolic syndrome and oncogenesis

A Fodor, AL Lazar, C Buchman, B Tiperciuc… - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) represents a cluster of disorders that increase the risk of a
plethora of conditions, in particular type two diabetes, cardiovascular diseases, and certain …

[HTML][HTML] SPP1 functions as an enhancer of cell growth in hepatocellular carcinoma targeted by miR-181c

J Wang, F Hao, X Fei, Y Chen - American journal of translational …, 2019 - ncbi.nlm.nih.gov
Patients diagnosed with hepatocellular carcinoma (HCC) suffered a high risk of recurrence
and poor prognosis. Identification of differentially expressed genes (DEGs) in HCC provides …

miRNAs expression signature potentially associated with lymphatic dissemination in locally advanced prostate cancer

EA Pudova, GS Krasnov, KM Nyushko… - BMC Medical …, 2020 - Springer
Background Prostate cancer is one of the most common and socially significant cancers
among men. The aim of our study was to reveal changes in miRNA expression profiles …

Serum level of miR-142-3p predicts prognostic outcome for colorectal cancer following curative resection

W Gao, D Pang, S Yu - Journal of International Medical …, 2019 - journals.sagepub.com
Objective MicroRNA (miR)-142-3p may function as a tumor suppressor in the development
of various cancers. In this study, we measured serum levels of miR-142-3p in patients with …

miR-1294 alleviates epithelial–mesenchymal transition by repressing FOXK1 in gastric cancer

Y Wang, G Liu, S Sun, J Qin - Genes & genomics, 2020 - Springer
Background MicroRNAs (miRNAs) have been reported play critical roles in regulating tumor
development and progression. Objective This study aimed to investigate the potential effect …

MicroRNA‑655 suppresses cell proliferation and invasion in oral squamous cell carcinoma by directly targeting metadherin and regulating the PTEN/AKT pathway …

Q Wang, L Lv, Y Li, H Ji - Molecular Medicine Reports, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) are important regulators of a variety of biological processes and their
dysregulation is closely related to cancer formation and progression. Therefore, examination …

[HTML][HTML] MicroRNA-181c suppresses the biological progression of osteosarcoma via targeting SMAD7 and regulating transforming growth factor-β (TGF-β) signaling …

Y Fu, Y Tang, J Wang, Z Guo - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
Background Osteosarcoma is a primary bone aggressive cancer, affecting adolescents
worldwide. Increasing evidence suggests that dysfunction of microRNAs (miRNAs) plays a …

[HTML][HTML] Endoscopic techniques for diagnosis and treatment of gastro-entero-pancreatic neuroendocrine neoplasms: Where we are

RE Rossi, A Elvevi, C Gallo, A Palermo… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND The correct localization of the primary tumor site and a complete
histological diagnosis represent the milestones for the proper management of gastro-entero …