Nanoparticle systems for cancer phototherapy: An overview

TP Pivetta, CEA Botteon, PA Ribeiro, PD Marcato… - Nanomaterials, 2021 - mdpi.com
Photodynamic therapy (PDT) and photothermal therapy (PTT) are photo-mediated
treatments with different mechanisms of action that can be addressed for cancer treatment …

Lab-on-a-DNA origami: nanoengineered single-molecule platforms

S Kogikoski, J Ameixa, A Mostafa, I Bald - Chemical Communications, 2023 - pubs.rsc.org
DNA origami nanostructures are self-assembled into almost arbitrary two-and three-
dimensional shapes from a long, single-stranded viral scaffold strand and a set of short …

The potential of DNA origami to build multifunctional materials

K Tapio, I Bald - Multifunctional Materials, 2020 - iopscience.iop.org
The development of the DNA origami technique has revolutionized the field of DNA
nanotechnology as it allows to create virtually any arbitrarily shaped nanostructure out of …

Low-energy (5–20 eV) electron-induced single and double strand breaks in well-defined DNA sequences

K Ebel, I Bald - The Journal of Physical Chemistry Letters, 2022 - ACS Publications
Ionizing radiation is used in cancer radiation therapy to effectively damage the DNA of
tumors. The main damage is due to generation of highly reactive secondary species such as …

Unraveling the Complexity of DNA Radiation Damage Using DNA Nanotechnology

J Ameixa, I Bald - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Radiation cancer therapies use different ionizing radiation qualities that
damage DNA molecules in tumor cells by a yet not completely understood plethora of …

Damage Induced to DNA and Its Constituents by 0–3 eV UV Photoelectrons

C Liu, Y Zheng, L Sanche - Photochemistry and Photobiology, 2022 - Wiley Online Library
The complex physical and chemical interactions between DNA and 0–3 eV electrons
released by UV photoionization can lead to the formation of various lesions such as base …

Vacuum‐UV and Low‐Energy Electron‐Induced DNA Strand Breaks–Influence of the DNA Sequence and Substrate

S Vogel, K Ebel, RM Schürmann, C Heck… - …, 2019 - Wiley Online Library
DNA is effectively damaged by radiation, which can on the one hand lead to cancer and is
on the other hand directly exploited in the treatment of tumor tissue. DNA strand breaks are …

Quasi-Free Electron-Mediated Radiation Sensitization by C5-Halopyrimidines

J Ma, T Bahry, SA Denisov, A Adhikary… - The Journal of …, 2021 - ACS Publications
Substitution of the thymidine moiety in DNA by C5-substituted halogenated thymidine
analogues causes significant augmentation of radiation damage in living cells. However, the …

Surprising Radiolytic Stability of 8-Thiomethyladenine in an Aqueous Solution

M Datta, A Szczyrba, M Zdrowowicz… - The Journal of …, 2024 - ACS Publications
8-Thiomethyladenine (ASCH3), a potentially radiosensitizing modified nucleobase, has
been synthesized in a reaction between 8-thioadenine and methyl iodide. Despite favorable …

Radiation and DNA Origami Nanotechnology: Probing Structural Integrity at the Nanoscale

J Ameixa, L Sala, J Kocisek, I Bald - ChemPhysChem, 2024 - Wiley Online Library
DNA nanotechnology has emerged as a groundbreaking field, using DNA as a scaffold to
create nanostructures with customizable properties. These DNA nanostructures hold …