A biomarker-based detection improves early diagnosis and subsequent treatment of
diseases. Chemo/biosensing and bioimaging play a crucial role in biomarker detection …

Conspectus Enzymes are a class of important substances for life, and their abnormal levels
are associated with many diseases. Thus, great progress has been made in the past decade …

Fluorescent probes have long been valuable tools in the study of biological systems. With
the ever-expanding range of known enzymatic biomarkers for disease, it has never been …

The accurate determination of specific biomolecules and their monitoring in complex
biological systems will help us understand their role in the body. In comparison with …

Over the last few years, the development of fluorescent probes has received considerable
attention. Fluorescence signaling allows noninvasive and harmless real-time imaging with …

Intensive development of optical (colorimetric/fluorescent) chemosensors is the landmark of
successful research efforts made after the advent of supramolecular chemistry. Amongst …

Tyrosinase (TYR, EC 1.14. 18.1), a critical enzyme participating in melanogenesis, catalyzes
the first two steps in melanin biosynthesis including the ortho-hydroxylation of L-tyrosine and …

Tyrosinase is an important enzyme in controlling the formation of melanin in melanosome,
and plays key a role in the pigmentation of hair and skin. The abnormal expression or …

Using the commercially available and economical 6-hydroxycoumarin (6-HC) as the
substrate, a dual-emission ratiometric fluorescence sensor was developed to detect …

Tyrosinase (Tyr) is known as an important cancer-related biomarker, which shows significant
over-expression in malignant tumor cells, such as melanoma. Developing highly sensitive …