[HTML][HTML] Potassium channels as a target for cancer therapy: Current perspectives
Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …
Ion channels and transporters as therapeutic agents: from biomolecules to supramolecular medicinal chemistry
G Picci, S Marchesan, C Caltagirone - Biomedicines, 2022 - mdpi.com
Ion channels and transporters typically consist of biomolecules that play key roles in a large
variety of physiological and pathological processes. Traditional therapies include many ion …
variety of physiological and pathological processes. Traditional therapies include many ion …
[PDF][PDF] Venoms classification and therapeutic uses: a narrative review.
The mere glimpse of venomous animals has always terrified humans because of the
devastating effects of their venoms. However, researchers across the globe have isolated …
devastating effects of their venoms. However, researchers across the globe have isolated …
The bee venom active compound melittin protects against bicuculline-induced seizures and hippocampal astrocyte activation in rats
B Soares-Silva, JIA Beserra-Filho, PMA Morera… - Neuropeptides, 2022 - Elsevier
Epilepsy is a chronic neuropathology characterized by an abnormal hyperactivity of neurons
that generate recurrent, spontaneous, paradoxical and synchronized nerve impulses …
that generate recurrent, spontaneous, paradoxical and synchronized nerve impulses …
Venom production and secretion in reptiles
SP Mackessy - Journal of Experimental Biology, 2022 - journals.biologists.com
The venom glands of reptiles, particularly those of front-fanged advanced snakes, must
satisfy conflicting biological demands: rapid synthesis of potentially labile and highly toxic …
satisfy conflicting biological demands: rapid synthesis of potentially labile and highly toxic …
Role of potassium ion channels in epilepsy: Focus on current therapeutic strategies
R Khan, P Chaturvedi, P Sahu… - CNS & Neurological …, 2024 - benthamdirect.com
Background Epilepsy is one of the prevalent neurological disorders characterized by
disrupted synchronization between inhibitory and excitatory neurons. Disturbed membrane …
disrupted synchronization between inhibitory and excitatory neurons. Disturbed membrane …
Innovative treatments for epilepsy: Venom peptides, cannabinoids, and neurostimulation
LS Lima, V Loyola, JVML Bicca, L Faro… - Journal of …, 2022 - Wiley Online Library
Antiepileptic drugs have been successfully treating epilepsy and providing individuals
sustained seizure freedom. However, about 30% of the patients with epilepsy present drug …
sustained seizure freedom. However, about 30% of the patients with epilepsy present drug …
Pathophysiology to Risk Factor and Therapeutics to Treatment Strategies on Epilepsy
APA Boleti, PHO Cardoso, BEF Frihling… - Brain Sciences, 2024 - mdpi.com
Epilepsy represents a condition in which abnormal neuronal discharges or the
hyperexcitability of neurons occur with synchronicity, presenting a significant public health …
hyperexcitability of neurons occur with synchronicity, presenting a significant public health …
How to Overcome a Snail? Identification of Putative Neurotoxins of Snail-Feeding Firefly Larvae (Coleoptera: Lampyridae, Lampyris noctiluca)
The larvae of some lampyrid beetles are highly specialized predators of snails. They have
been observed to climb on the shells of their prey and use this exposed position to bite and …
been observed to climb on the shells of their prey and use this exposed position to bite and …
[HTML][HTML] Revealing the Bioactivities of Physalia physalis Venom Using Drosophila as a Model
Z Tomkielska, J Frias, N Simões, BP de Bastos… - Toxins, 2024 - mdpi.com
Physalia physalis, commonly known as the Portuguese Man o'War, is one of the most
venomous members of the Cnidaria yet is poorly understood. This article investigates the …
venomous members of the Cnidaria yet is poorly understood. This article investigates the …