Regulated cell death (RCD) in cancer: key pathways and targeted therapies
F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …
form of cell death that can be regulated by a variety of biomacromolecules, which is …
Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling
SC Koeberle, AP Kipp, H Stuppner… - Medicinal Research …, 2023 - Wiley Online Library
Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid
peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight …
peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight …
Ferroptosis and its role in chronic diseases
W Hu, K Liang, H Zhu, C Zhao, H Hu, S Yin - Cells, 2022 - mdpi.com
Ferroptosis, which has been widely associated with many diseases, is an iron-dependent
regulated cell death characterized by intracellular lipid peroxide accumulation. It exhibits …
regulated cell death characterized by intracellular lipid peroxide accumulation. It exhibits …
Ferroptosis in gastrointestinal cancer: from mechanisms to implications
Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …
that results in plasma membrane damage and the release of damage-associated molecular …
Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma
L Zhu, F Yang, L Wang, L Dong, Z Huang… - Cancer cell …, 2021 - Springer
Background Ferroptosis is a recently recognized non-apoptotic cell death that is distinct from
the apoptosis, necroptosis and pyroptosis. Considerable studies have demonstrated …
the apoptosis, necroptosis and pyroptosis. Considerable studies have demonstrated …
Ferroptosis in colorectal cancer: a future target?
Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide and is
characterised by frequently mutated genes, such as APC, TP53, KRAS and BRAF. The …
characterised by frequently mutated genes, such as APC, TP53, KRAS and BRAF. The …
Curcumin and andrographis exhibit anti-tumor effects in colorectal cancer via activation of ferroptosis and dual suppression of glutathione peroxidase-4 and …
Colorectal cancer (CRC) is the leading cause of cancer-related deaths worldwide. The
limitations of current chemotherapeutic drugs in CRC include their toxicity, side effects, and …
limitations of current chemotherapeutic drugs in CRC include their toxicity, side effects, and …
[HTML][HTML] Ferroptosis-based nano delivery systems targeted therapy for colorectal cancer: insights and future perspectives
C Qiao, H Wang, Q Guan, M Wei, Z Li - Asian Journal of Pharmaceutical …, 2022 - Elsevier
There are limited options for patients who develop liver metastasis from colorectal cancer
(CRC), the leading cause of cancer-related mortality worldwide. Emerging evidence has …
(CRC), the leading cause of cancer-related mortality worldwide. Emerging evidence has …
Enhanced anti-cancer activity of andrographis with oligomeric proanthocyanidins through activation of metabolic and ferroptosis pathways in colorectal cancer
The high degree of morbidity and mortality in colorectal cancer (CRC) patients is largely due
to the development of chemoresistance against conventional chemotherapeutic drugs. In …
to the development of chemoresistance against conventional chemotherapeutic drugs. In …
Comprehensive analysis of immune infiltrates of ferroptosis‐related long noncoding RNA and prediction of colon cancer patient prognoses
W Chen, Y Chen, L Liu, Y Wu, P Fu… - Journal of …, 2022 - Wiley Online Library
Ferroptosis is a newly defined mode of programmed oxidative cell death. Knowledge of
ferroptosis‐related long noncoding (lnc) RNA in the tumor immune microenvironment of …
ferroptosis‐related long noncoding (lnc) RNA in the tumor immune microenvironment of …