The foundation of antibiotic discovery was laid by Paul Ehrlich in 1906 with the discovery of
compound 606, a gold powder, after the systematic screening approach including hundreds …

Staphylococcus species are one of the major causes of bacterial bloodstream infections.
Multi-resistant staphylococci infections are major therapeutic problems. This study was …

Counting from the fist clinical use of penicillin on the soldiers of World War II, antibiotic
resistance has now been 75 years old global issue. During this period numerous antibiotics …

Abstract Background and Objectives: Coagulase negative Staphylococci (CoNS) are
colonizers of the skin, anterior nares, and ear canals of human beings. They have long been …

Linezolid is one of the most potent antibacterial agents against gram positive organisms
especially used in the treatment of skin and soft tissue infections and hospital acquired …

Background: Staphylococcus aureus has become increasingly prevalent in recent decades,
serving as a primary source of infections acquired in both hospital and community settings …

RESUMO A inibição do metabolismo do folato é uma importante estratégia no tratamento de
doenças infecciosas. No metabolismo do folato, a enzima diidrofolato redutase (DHFR) …

BACKGROUND Staphylococcus aureusis one of the most prevalent and clinically significant
pathogens causing wide variety of infections ranging from mild skin and soft tissue infections …