Molecular control of oligodendrocyte development
Myelin is a multilayer lipid membrane structure that wraps and insulates axons, allowing for
the efficient propagation of action potentials. During developmental myelination of the …
the efficient propagation of action potentials. During developmental myelination of the …
The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
From OPC to oligodendrocyte: an epigenetic journey
Oligodendrocytes provide metabolic and functional support to neuronal cells, rendering
them key players in the functioning of the central nervous system. Oligodendrocytes need to …
them key players in the functioning of the central nervous system. Oligodendrocytes need to …
[HTML][HTML] Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview
Multiple sclerosis (MS) is a leading cause of progressive disability among young adults
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …
MicroRNAs, multiple sclerosis, and depression
H Wang - International Journal of Molecular Sciences, 2021 - mdpi.com
Multiple sclerosis (MS) is a chronic disease of the central nervous system that affects the
brain and spinal cord. There are several disease courses in MS including relapsing …
brain and spinal cord. There are several disease courses in MS including relapsing …
Remyelination in multiple sclerosis from the miRNA perspective
K Maciak, A Dziedzic, J Saluk - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Remyelination relies on the repair of damaged myelin sheaths, involving microglia cells,
oligodendrocyte precursor cells (OPCs), and mature oligodendrocytes. This process drives …
oligodendrocyte precursor cells (OPCs), and mature oligodendrocytes. This process drives …
Multiple sclerosis: roles of miRNA, lcnRNA, and circRNA and their implications in cellular pathways
GL Cipriano, G Schepici, E Mazzon… - International Journal of …, 2024 - mdpi.com
Multiple sclerosis (MS) is a degenerative condition characterized by axonal damage and
demyelination induced by autoreactive immune cells that occur in the Central Nervous …
demyelination induced by autoreactive immune cells that occur in the Central Nervous …
In vivo silencing of miR‐125a‐3p promotes myelin repair in models of white matter demyelination
In the last decade, microRNAs have been increasingly recognized as key modulators of glial
development. Recently, we identified miR‐125a‐3p as a new player in oligodendrocyte …
development. Recently, we identified miR‐125a‐3p as a new player in oligodendrocyte …
Extracellular vesicle‐associated cholesterol supports the regenerative functions of macrophages in the brain
S Vanherle, J Guns, M Loix, F Mingneau… - Journal of …, 2023 - Wiley Online Library
Macrophages play major roles in the pathophysiology of various neurological disorders,
being involved in seemingly opposing processes such as lesion progression and resolution …
being involved in seemingly opposing processes such as lesion progression and resolution …