In this review, we shall describe the rich crosstalk between non-receptor Src-family kinases
(SFKs) and the Ca 2+ transient generated in activated cells by a variety of extracellular and …

Preterm labor leading to preterm birth is the leading cause of infant morbidity and mortality.
At the present time, nothing can reliably halt labor once it begins. The knowledge that …

Colorectal cancer (CRC) is the third most prevalent human cancer globally. 5-Fluorouracil (5-
FU)-based systemic chemotherapy is the primary strategy for advanced CRC treatment, yet …

Over the last three decades, neoplasms have become the largest cause of human mortality
due to both high tumor incidence and mortality. Chemotherapy is one of the main therapies …

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with
few treatment options. A promising TNBC treatment approach is targeting the oncogenic …

Src kinase has long been recognized as a factor in the progression of colorectal cancer and
seems to play a specific role in the development of the metastatic phenotype. In spite of …

Fibroblasts transformed by the v-Src oncoprotein exhibit elevated activity of the enzyme
phosphatidylinositol 3′-kinase (PI 3-kinase), which binds to, and is activated by, a wide …

Virus replication and spreading in a host population depends on highly specific interactions
of viral proteins with infected cells, resulting in subversion of multiple cellular signal …

1 2014NCCN 子宫肿瘤临床实践指南(第1 版) 主要更新(1) 增加了子宫内膜癌手术分期及评估
原则.(2) 增加了早期子宫内膜样腺癌患者保留生育功能的指征和方法.(3) 增加了子宫内膜样腺癌 …

The mechanism of v-src-induced morphological transformation is still obscure. We
compared LA29 rat fibroblasts, which express a temperature-sensitive (ts) v-src mutant, with …