Recent progress and prospects in catalytic water treatment
Presently, conventional technologies in water treatment are not efficient enough to
completely mineralize refractory water contaminants. In this context, the implementation of …
completely mineralize refractory water contaminants. In this context, the implementation of …
[HTML][HTML] Non-Noble Metal Aromatic Oxidation Catalysis: From Metalloenzymes to Synthetic Complexes
E Masferrer-Rius, RJM Klein Gebbink - Catalysts, 2023 - mdpi.com
The development of selective aromatic oxidation catalysts based on non-noble metals has
emerged over the last decades, mainly due to the importance of phenol products as …
emerged over the last decades, mainly due to the importance of phenol products as …
A Comparative Study of Molecular Structure, pKa, Lipophilicity, Solubility, Absorption and Polar Surface Area of Some Antiplatelet Drugs
Theoretical chemistry methods have been used to study the molecular properties of
antiplatelet agents (ticlopidine, clopidogrel, prasugrel, elinogrel, ticagrelor and cangrelor) …
antiplatelet agents (ticlopidine, clopidogrel, prasugrel, elinogrel, ticagrelor and cangrelor) …
[图书][B] Cytochrome P450 2D6: structure, function, regulation and polymorphism
S Zhou - 2018 - taylorfrancis.com
Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic
pathways and are classified in various superfamilies. The CYP, or P450, superfamily …
pathways and are classified in various superfamilies. The CYP, or P450, superfamily …
Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in …
Crystal structures of CYP2B35 and CYP2B37 from the desert woodrat were solved in
complex with 4-(4-chlorophenyl) imidazole (4-CPI). The closed conformation of CYP2B35 …
complex with 4-(4-chlorophenyl) imidazole (4-CPI). The closed conformation of CYP2B35 …
Ordered chimerogenesis applied to CYP2B P450 enzymes
Background Structural studies on CYP2B enzymes identified some of the features that are
related to their high plasticity. The aim of this work was to understand further the possible …
related to their high plasticity. The aim of this work was to understand further the possible …
Polymorphism in S (+) Clopidogrel-Picrate: Insights from X-ray Diffraction, Vibrational Spectroscopy, Thermal Analysis, and Quantum Chemistry
A Cvetkovski, P Makreski, L Pejov… - Crystals, 2023 - mdpi.com
The crystal structures of two pseudopolymorphic forms of S (+) clopidogrel–picrate are
reported. Form 1 crystallizes in the monoclinic space group P 21 with an ionic couple S (+) …
reported. Form 1 crystallizes in the monoclinic space group P 21 with an ionic couple S (+) …
A structural snapshot of CYP2B4 in complex with paroxetine provides insights into ligand binding and clusters of conformational states
MB Shah, I Kufareva, J Pascual, Q Zhang… - … of Pharmacology and …, 2013 - ASPET
An X-ray crystal structure of CYP2B4 in complex with the drug paroxetine [(3 S, 4 R)-3-[(2 H-
1, 3-benzodioxol-5-yloxy) methyl]-4-(4-fluorophenyl) piperidine] was solved at 2.14 Å …
1, 3-benzodioxol-5-yloxy) methyl]-4-(4-fluorophenyl) piperidine] was solved at 2.14 Å …
Multiresolution molecular dynamics simulations reveal the interplay between conformational variability and functional interactions in membrane-bound cytochrome …
SB Han, J Teuffel, G Mukherjee, RC Wade - bioRxiv, 2024 - biorxiv.org
Cytochrome P450 2B4 (CYP 2B4) is one of the best characterized CYPs and serves as a
key model system for understanding the mechanisms of microsomal class II CYPs, which …
key model system for understanding the mechanisms of microsomal class II CYPs, which …
Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes
HH Jang, J Liu, GY Lee, JR Halpert… - Archives of biochemistry …, 2015 - Elsevier
The functional importance of a peripheral pocket found in previously published X-ray crystal
structures of CYP2B4 and CYP2B6 was probed using a biophysical approach. Introduction …
structures of CYP2B4 and CYP2B6 was probed using a biophysical approach. Introduction …