Ferrosenescence: the iron age of neurodegeneration?
Aging has been associated with iron retention in many cell types, including the neurons,
promoting neurodegeneration by ferroptosis. Excess intracellular iron accelerates aging by …
promoting neurodegeneration by ferroptosis. Excess intracellular iron accelerates aging by …
The regulatory impact of RNA-binding proteins on microRNA targeting
Argonaute is the primary mediator of metazoan miRNA targeting (MT). Among the currently
identified> 1,500 human RNA-binding proteins (RBPs), there are only a handful of RBPs …
identified> 1,500 human RNA-binding proteins (RBPs), there are only a handful of RBPs …
miR-206/133b cluster: a weapon against lung cancer?
Lung cancer is a deadly disease that ends numerous lives around the world. MicroRNAs
(miRNAs) are a group of non-coding RNAs involved in a variety of biological processes …
(miRNAs) are a group of non-coding RNAs involved in a variety of biological processes …
[HTML][HTML] Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators
M Geretto, A Pulliero, C Rosano… - American journal of …, 2017 - ncbi.nlm.nih.gov
Chemo-resistance, which is the main obstacle in cancer therapy, is caused by the onset of
drug-resistant cells in the heterogeneous cell population in cancer tissues. MicroRNAs …
drug-resistant cells in the heterogeneous cell population in cancer tissues. MicroRNAs …
MiRNA-based therapeutic strategy in lung cancer
G Li, J Fang, Y Wang, H Wang… - Current pharmaceutical …, 2017 - ingentaconnect.com
Lung cancer is one of the most common malignant tumors in the world. Although advanced
therapies have been applied for the treatment of lung cancer, the prolongation of overall …
therapies have been applied for the treatment of lung cancer, the prolongation of overall …
Peptides as epigenetic modulators: therapeutic implications
Y Janssens, E Wynendaele, W Vanden Berghe… - Clinical …, 2019 - Springer
Peptides originating from different sources (endogenous, food derived, environmental, and
synthetic) are able to influence different aspects of epigenetic regulation. Endogenous short …
synthetic) are able to influence different aspects of epigenetic regulation. Endogenous short …
Antibiotics-peptide conjugates against multidrug-resistant bacterial pathogens
The menace of multi-drug resistance by bacterial pathogens that are responsible for
infectious diseases in humans and animals cannot be over-emphasized. Many bacteria …
infectious diseases in humans and animals cannot be over-emphasized. Many bacteria …
[HTML][HTML] Trading places: Peptide and small molecule alternatives to oligonucleotide-based modulation of microRNA expression
It is well established that microRNA (miRNA) dysregulation is involved in the development
and progression of various diseases, especially cancer. Emerging evidence suggests that …
and progression of various diseases, especially cancer. Emerging evidence suggests that …
miR‑29b suppresses proliferation and induces apoptosis of hepatocellular carcinoma ascites H22 cells via regulating TGF‑β1 and p53 signaling pathway
YL Liu, WH Yang, BY Chen, J Nie… - International …, 2021 - spandidos-publications.com
Abstract MicroRNA (miR)‑29b is a key tumor regulator. It can inhibit tumor cell proliferation,
induce apoptosis, suppress tumor invasion and migration, thus delaying tumor progression …
induce apoptosis, suppress tumor invasion and migration, thus delaying tumor progression …
Role of Epigenetics in Human Diseases
FA Azami, M Eslami, AM Ardekani - Molecular Mechanisms of …, 2023 - books.google.com
Epigenetic processes have been defined as heritable changes in gene expression and
chromatin structure without alternating coding sequences (1). Epigenetic changes are …
chromatin structure without alternating coding sequences (1). Epigenetic changes are …