[HTML][HTML] Recent advances in understanding necrotizing enterocolitis

M Alganabi, C Lee, E Bindi, B Li, A Pierro - F1000Research, 2019 - ncbi.nlm.nih.gov
Necrotizing enterocolitis is a devastating intestinal disease affecting preterm infants. In spite
of ongoing research and advancement in neonatal care, mortality remains high, especially …

Bioresponsive drug delivery systems in intestinal inflammation: State-of-the-art and future perspectives

NG Kotla, S Rana, G Sivaraman, O Sunnapu… - Advanced drug delivery …, 2019 - Elsevier
Oral colon-specific delivery systems emerged as the main therapeutic cargos by making a
significant impact in the field of modern medicine for local drug delivery in intestinal …

Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis

B Li, A Hock, RY Wu, A Minich, SR Botts, C Lee… - PLoS one, 2019 - journals.plos.org
Necrotizing enterocolitis (NEC) is characterized by intestinal injury and impaired mucin
synthesis. We recently showed that breast milk exosomes from rodents promote intestinal …

[HTML][HTML] Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature

AR Silini, R Di Pietro, I Lang-Olip, F Alviano… - … in bioengineering and …, 2020 - frontiersin.org
Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …

Concise review: amniotic fluid stem cells: the known, the unknown, and potential regenerative medicine applications

SP Loukogeorgakis, P De Coppi - Stem Cells, 2017 - academic.oup.com
The amniotic fluid has been identified as an untapped source of cells with broad potential,
which possess immunomodulatory properties and do not have the ethical and legal …

Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Y Koike, B Li, N Ganji, H Zhu, H Miyake, Y Chen… - Nature …, 2020 - nature.com
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high
mortality rate, indicating the need for precision treatment. NEC is characterized by intestinal …

Breastmilk cell trafficking induces microchimerism‐mediated immune system maturation in the infant

JP Molès, E Tuaillon, C Kankasa… - Pediatric allergy and …, 2018 - Wiley Online Library
Initiating breastfeeding within the first hour of life confers an important benefit in terms of
child mortality and severe morbidity. Intestinal permeability to ingested macromolecules and …

First characterization of human amniotic fluid stem cell extracellular vesicles as a powerful paracrine tool endowed with regenerative potential

C Balbi, M Piccoli, L Barile, A Papait… - Stem cells …, 2017 - academic.oup.com
Human amniotic fluid stem cells (hAFS) have shown a distinct secretory profile and
significant regenerative potential in several preclinical models of disease. Nevertheless, little …

Current research on the epidemiology, pathogenesis, and management of necrotizing enterocolitis

S Eaton, CM Rees, NJ Hall - Neonatology, 2017 - karger.com
Despite decades of research on necrotizing enterocolitis, we still do not fully understand the
pathogenesis of the disease, or how to prevent or how to treat it. However, as a result of …

Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents

L Antounians, VD Catania, L Montalva, BD Liu… - Science translational …, 2021 - science.org
Fetal lung underdevelopment, also known as pulmonary hypoplasia, is characterized by
decreased lung growth and maturation. The most common birth defect found in babies with …