Recent advances in microfluidics-based cell migration research

J Ren, N Wang, P Guo, Y Fan, F Lin, J Wu - Lab on a Chip, 2022 - pubs.rsc.org
Cell migration is crucial for many biological processes, including normal development,
immune response, and tissue homeostasis and many pathological processes such as …

Organ-on-chip technology: the future of feto-maternal interface research?

L Richardson, S Kim, R Menon, A Han - Frontiers in Physiology, 2020 - frontiersin.org
The placenta and fetal membrane act as a protective barrier throughout pregnancy while
maintaining communication and nutrient exchange between the baby and the mother …

Microfabricated tuneable and transferable porous PDMS membranes for Organs-on-Chips

WF Quirós-Solano, N Gaio, O Stassen, YB Arik… - Scientific reports, 2018 - nature.com
We present a novel and highly reproducible process to fabricate transferable porous PDMS
membranes for PDMS-based Organs-on-Chips (OOCs) using microelectromechanical …

Investigations on T cell transmigration in a human skin-on-chip (SoC) model

X Ren, AE Getschman, S Hwang, BF Volkman… - Lab on a Chip, 2021 - pubs.rsc.org
A microfluidics-based three-dimensional skin-on-chip (SoC) model is developed in this
study to enable quantitative studies of transendothelial and transepithelial migration of …

Novel strategies in artificial organ development: what is the future of medicine?

M Klak, T Bryniarski, P Kowalska, M Gomolka… - Micromachines, 2020 - mdpi.com
The technology of tissue engineering is a rapidly evolving interdisciplinary field of science
that elevates cell-based research from 2D cultures through organoids to whole bionic …

A Comprehensive Review of Biosensor Integration in Microphysiological Systems for Online Monitoring: Current Challenges and Future Advancements

F Hussain Memon, K Inseok, F Ahmed… - ChemBioEng …, 2023 - Wiley Online Library
The goal of microphysiological systems (MPS) is to replicate the relevant functionality of
human organ tissues in in vitro. MPS technology so far has been used to simulate the …

Enhanced Cell Viability and Migration of Primary Bovine Annular Fibrosus Fibroblast-like Cells Induced by Microsecond Pulsed Electric Field Exposure

PM Atsu, C Mowen, GL Thompson - ACS omega, 2023 - ACS Publications
This study is the first to report the enhancement of cell migration and proliferation induced by
in vitro microsecond pulsed electric field (μsPEF) exposure of primary bovine annulus …

Degenerative disease‐on‐a‐chip: Developing microfluidic models for rapid availability of newer therapies

D Jahagirdar, P Bangde, R Jain… - Biotechnology …, 2021 - Wiley Online Library
Background Understanding the pathophysiology of degenerative diseases pertaining to
nervous system, ocular region, bone/cartilage, and muscle are still being comprehended …

Applications of microfluidic devices in advancing NK-cell migration studies

X Ren, A Alamri, J Hipolito, F Lin, SKP Kung - Methods in enzymology, 2020 - Elsevier
Understanding how NK cells interact with tumor cells under specific microenvironment will
be informative in development of NK-cell based immunotherapy. Applications of microfluidic …

Sputum from chronic obstructive pulmonary disease patients inhibits T cell migration in a microfluidic device

X Ren, J Wu, D Levin, S Santos… - Annals of the New …, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a common lung disease characterized by
narrowed airways, resulting in serious breathing difficulty. Previous studies have …