Changes in plasma free fatty acids associated with type-2 diabetes

A IS Sobczak, C A. Blindauer, A J. Stewart - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid
(FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms …

What is lipotoxicity?

AB Engin - Obesity and lipotoxicity, 2017 - Springer
Enlarged fat cells in obese adipose tissue diminish capacity to store fat and are resistant to
the anti-lipolytic effect of insulin. Insulin resistance (IR)-associated S-nitrosylation of insulin …

Plasma lipid profiling in a large population-based cohort [S]

JM Weir, G Wong, CK Barlow, MA Greeve… - Journal of lipid …, 2013 - ASBMB
We have performed plasma lipid profiling using liquid chromatography electrospray
ionization tandem mass spectrometry on a population cohort of more than 1,000 individuals …

Fish oil—how does it reduce plasma triglycerides?

GC Shearer, OV Savinova, WS Harris - … BBA)-Molecular and Cell Biology of …, 2012 - Elsevier
Long chain omega-3 fatty acids (FAs) are effective for reducing plasma triglyceride (TG)
levels. At the pharmaceutical dose, 3.4 g/day, they reduce plasma TG by about 25–50% after …

[PDF][PDF] Excess of free fatty acids as a cause of metabolic dysfunction in skeletal muscle

J Tumova, M Andel, J Trnka - Physiological research, 2016 - researchgate.net
Obesity is often associated with metabolic impairments in peripheral tissues. Evidence
suggests an excess of free fatty acids (FFA) as one factor linking obesity and related …

Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells

RA Vaughan, R Garcia-Smith, M Bisoffi… - Lipids in health and …, 2012 - Springer
Background Polyunsaturated fatty acids are popular dietary supplements advertised to
contribute to weight loss by increasing fat metabolism in liver, but the effects on overall …

Metabolomics in newborns with intrauterine growth retardation (IUGR): urine reveals markers of metabolic syndrome

A Dessì, L Atzori, A Noto… - The Journal of …, 2011 - Taylor & Francis
To date, we have little knowledge on the overall metabolic status of neonates with
intrauterine growth retardation (IUGR). In the last few years, the analysis of metabolomics …

Lipid-induced insulin resistance in skeletal muscle: the chase for the culprit goes from total intramuscular fat to lipid intermediates, and finally to species of lipid …

SM Kitessa, MY Abeywardena - Nutrients, 2016 - mdpi.com
The skeletal muscle is the largest organ in the body. It plays a particularly pivotal role in
glucose homeostasis, as it can account for up to 40% of the body and for up to 80%–90% of …

[HTML][HTML] Fit with good fat? The role of n-3 polyunsaturated fatty acids on exercise performance

M Da Boit, AM Hunter, SR Gray - Metabolism, 2017 - Elsevier
Abstract N-3 PUFA (n-3) polyunsaturated fatty acids (PUFA) are a family of fatty acids mainly
found in oily fish and fish oil supplements. The effects of n-3 PUFA on health are mainly …

[图书][B] Sphingolipids in obesity, type 2 diabetes, and metabolic disease

SB Russo, JS Ross, LA Cowart - 2013 - Springer
Metabolic disease, including obesity and type 2 diabetes, constitutes a major emerging
health crisis in Western nations. Although the symptoms and clinical pathology and …