Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Pathophysiology and histopathology of primary aldosteronism

TA Williams, M Reincke - Trends in Endocrinology & Metabolism, 2022 - cell.com
Primary aldosteronism (PA) can be sporadic or familial and classified into unilateral and
bilateral forms. Sporadic PA predominates with excessive aldosterone production usually …

Heightened cardiovascular risk in hypertension associated with renin‐independent aldosteronism versus renin‐dependent aldosteronism: a collaborative study

J Hu, H Shen, P Huo, J Yang, PJ Fuller… - Journal of the …, 2021 - Am Heart Assoc
Background While both renin‐dependent and renin‐independent aldosterone secretion
contribute to aldosteronism, their relative associations with cardiovascular disease (CVD) …

[HTML][HTML] Radiomics utilization to differentiate nonfunctional adenoma in essential hypertension and functional adenoma in primary aldosteronism

PT Chen, D Chang, KL Liu, WC Liao, W Wang… - Scientific Reports, 2022 - nature.com
We performed the present study to investigate the role of computed tomography (CT)
radiomics in differentiating nonfunctional adenoma and aldosterone-producing adenoma …

[HTML][HTML] Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism

H Kaneko, H Umakoshi, M Ogata, N Wada, T Ichijo… - Scientific reports, 2022 - nature.com
Unilateral subtype of primary aldosteronism (PA) is a common surgically curable form of
endocrine hypertension. However, more than half of the patients with PA who undergo …

Prognostic models to predict complete resolution of hypertension after adrenalectomy in primary aldosteronism: A systematic review and meta‐analysis

L Marzano, A Kazory, F Husain‐Syed… - Clinical …, 2023 - Wiley Online Library
Complete resolution of hypertension (CRH) after adrenalectomy for primary aldosteronism is
far from a certainty. Although several prognostic models have been proposed to predict …

Assessment of performance of stratum-specific likelihood ratios of the aldosteronoma resolution score for predicting hypertension cure after adrenalectomy for primary …

L Marzano, F Husain-Syed, T Reis, C Ronco… - Journal of Human …, 2023 - nature.com
Abstract The Aldosteronoma Resolution Score (ARS) is the most studied scoring system for
predicting the high likelihood of hypertension cure after adrenalectomy for unilateral primary …

[HTML][HTML] Surgical quality, antihypertensive therapy, and electrolyte balance: A novel trifecta to assess long-term outcomes of adrenal surgery for unilateral primary …

U Anceschi, M Mormando, C Fiori, O Zappalà… - Journal of Clinical …, 2022 - mdpi.com
Background: To propose a trifecta that summarizes endpoints and predicts their
maintenance after adrenalectomy (n= 90) for unilateral primary aldosteronism (UPA) …

[HTML][HTML] The therapeutic intensity score as predictor of clinical outcomes after total and partial adrenalectomy for unilateral primary aldosteronism: results of a …

U Anceschi, M Mormando, RS Flammia, C Fiori… - Journal of Clinical …, 2023 - mdpi.com
Background: To evaluate the ability of therapeutic intensity score (TIS) in predicting the
clinical outcomes of partial (PA) and total adrenalectomy (TA) for UPA. Methods: Between …

[HTML][HTML] Predictive factors of clinical success after adrenalectomy in primary aldosteronism: A systematic review and meta-analysis

W Manosroi, P Atthakomol, P Phinyo… - Frontiers in …, 2022 - frontiersin.org
Background Unilateral adrenalectomy is the mainstay treatment for unilateral primary
aldosteronism (PA). This meta-analysis aimed to systematically analyse predictors of clinical …