Lipid nanocarriers as skin drug delivery systems: Properties, mechanisms of skin interactions and medical applications

M Sala, R Diab, A Elaissari, H Fessi - International journal of pharmaceutics, 2018 - Elsevier
During the past decades, lipid nanocarriers are gaining momentum with their multiple
advantages for the management of skin diseases. Lipid nanocarriers enable to target the …

Nano-formulations for transdermal drug delivery: A review

X Zhou, Y Hao, L Yuan, S Pradhan, K Shrestha… - Chinese Chemical …, 2018 - Elsevier
Transdermal drug delivery refers to a means of delivering drugs through the surface of the
skin for local or systemic treatment. The drug functions after absorption through the skin into …

Surfactant effects on lipid-based vesicles properties

R Bnyan, I Khan, T Ehtezazi, I Saleem, S Gordon… - Journal of …, 2018 - Elsevier
Understanding the effect of surfactant properties is critical when designing vesicular delivery
systems. This review evaluates previous studies to explain the influence of surfactant …

Cationic surfactants: Self-assembly, structure-activity correlation and their biological applications

LY Zakharova, TN Pashirova, S Doktorovova… - … Journal of Molecular …, 2019 - mdpi.com
The development of biotechnological protocols based on cationic surfactants is a modern
trend focusing on the fabrication of antimicrobial and bioimaging agents, supramolecular …

In vitro skin models as a tool in optimization of drug formulation

GE Flaten, Z Palac, A Engesland… - European journal of …, 2015 - Elsevier
Abstract (Trans) dermal drug therapy is gaining increasing importance in the modern drug
development. To fully utilize the potential of this route, it is important to optimize the delivery …

[HTML][HTML] Factors affecting liposomes particle size prepared by ethanol injection method

S Shaker, AR Gardouh, MM Ghorab - Research in pharmaceutical …, 2017 - journals.lww.com
Ethanol injection is one of the techniques frequently used to produce liposomes which
favors both simplicity and safety. In this process, an ethanolic solution of lipids is rapidly …

Investigating the targeting power to brain tissues of intranasal rasagiline mesylate-loaded transferosomal in situ gel for efficient treatment of Parkinson's disease

HN ElShagea, RR Makar, AH Salama, NA Elkasabgy… - Pharmaceutics, 2023 - mdpi.com
Rasagiline mesylate (RSM) is a hydrophilic drug with poor oral bioavailability (36%)
because of hepatic first-pass metabolism. The present study focuses on delivering RSM …

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far

MY Thanuja, C Anupama, SH Ranganath - Advanced drug delivery reviews, 2018 - Elsevier
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

Improved skin permeation of methotrexate via nanosized ultradeformable liposomes

A Zeb, OS Qureshi, HS Kim, JH Cha… - International journal of …, 2016 - Taylor & Francis
The aim of this study is to investigate methotrexate-entrapped ultradeformable liposomes
(MTX-UDLs) for potential transdermal application. MTX-UDLs were prepared by extrusion …

Design and characterization of spray-dried proliposomes for the pulmonary delivery of curcumin

IM Adel, MF ElMeligy, MEA Abdelrahim… - International journal …, 2021 - Taylor & Francis
Purpose The goal was to directly deliver curcumin, a natural polyphenolic anticancer and
anti-inflammatory compound, to the lung tissues with minimal systemic exposure through the …