Alveolar macrophages in the resolution of inflammation, tissue repair, and tolerance to infection

B Allard, A Panariti, JG Martin - Frontiers in immunology, 2018 - frontiersin.org
Pathogen persistence in the respiratory tract is an important preoccupation, and of particular
relevance to infectious diseases such as tuberculosis. The equilibrium between elimination …

Macrophage polarization and meta-inflammation

C Li, MM Xu, K Wang, AJ Adler, AT Vella, B Zhou - Translational Research, 2018 - Elsevier
Chronic overnutrition and obesity induces low-grade inflammation throughout the body.
Termed “meta-inflammation,” this chronic state of inflammation is mediated by macrophages …

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

AA Kapralov, Q Yang, HH Dar, YY Tyurina… - Nature chemical …, 2020 - nature.com
Ferroptotic death is the penalty for losing control over three processes—iron metabolism,
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …

A tough nitric oxide-eluting hydrogel coating suppresses neointimal hyperplasia on vascular stent

Y Chen, P Gao, L Huang, X Tan, N Zhou, T Yang… - Nature …, 2021 - nature.com
Vascular stent is viewed as one of the greatest advancements in interventional cardiology.
However, current approved stents suffer from in-stent restenosis associated with neointimal …

Cardiovascular risk factors and molecular routes underlying endothelial dysfunction: Novel opportunities for primary prevention

G Benincasa, E Coscioni, C Napoli - Biochemical Pharmacology, 2022 - Elsevier
One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …

Senescent cells: a therapeutic target for cardiovascular disease

BG Childs, H Li, JM Van Deursen - The Journal of clinical …, 2018 - Am Soc Clin Investig
Cellular senescence, a major tumor-suppressive cell fate, has emerged from humble
beginnings as an in vitro phenomenon into recognition as a fundamental mechanism of …

[HTML][HTML] Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: From effects to molecular mechanisms

Y Zeng, Y Xiong, T Yang, Y Wang, J Zeng… - Biomedicine & …, 2022 - Elsevier
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among all
types of diseases in the world, affecting many millions of individuals every year. CVD …

Current knowledge on the mechanism of atherosclerosis and pro-atherosclerotic properties of oxysterols

A Zmysłowski, A Szterk - Lipids in health and disease, 2017 - Springer
Due to the fact that one of the main causes of worldwide deaths are directly related to
atherosclerosis, scientists are constantly looking for atherosclerotic factors, in an attempt to …

Exploring the various aspects of the pathological role of vascular endothelial growth factor (VEGF) in diabetic retinopathy

T Behl, A Kotwani - Pharmacological research, 2015 - Elsevier
Diabetic retinopathy, a sight-threatening microvascular complication of diabetes mellitus, is
initiated by retinal endothelial dysfunction and succeeded by various pathological events …

[HTML][HTML] Nitric-oxide enriched plasma-activated water inactivates 229E coronavirus and alters antiviral response genes in human lung host cells

NK Kaushik, P Bhartiya, N Kaushik, Y Shin… - Bioactive materials, 2023 - Elsevier
The ongoing pandemic caused by the novel coronavirus, SARS-CoV-2, is influencing global
health. Moreover, there is a major threat of future coronaviruses affecting the entire world in …