[HTML][HTML] Recent advances in the medical applications of hemostatic materials

Y Guo, M Wang, Q Liu, G Liu, S Wang, J Li - Theranostics, 2023 - ncbi.nlm.nih.gov
Bleeding caused by trauma or surgery is a serious health problem, and uncontrollable
bleeding can result in death. Therefore, developing safe, effective, and convenient …

Opportunities and challenges of nanomaterials in wound healing: Advances, mechanisms, and perspectives

W Fu, S Sun, Y Cheng, J Ma, Y Hu, Z Yang… - Chemical Engineering …, 2024 - Elsevier
Wound healing is an intricate process that involves interactions between various types of
cell and molecular mechanisms. When wounds fail to heal effectively or develop into chronic …

Hemostatic agents for prehospital hemorrhage control: a narrative review

HT Peng - Military Medical Research, 2020 - Springer
Hemorrhage is the leading cause of preventable death in combat trauma and the secondary
cause of death in civilian trauma. A significant number of deaths due to hemorrhage occur …

Hemostasis strategies and recent advances in nanomaterials for hemostasis

J Du, J Wang, T Xu, H Yao, L Yu, D Huang - Molecules, 2023 - mdpi.com
The development of materials that effectively stop bleeding and prevent wound adhesion is
essential in both military and medical fields. However, traditional hemostasis methods, such …

Topical hemostatic materials for coagulopathy

B Hu, G Bao, X Xu, K Yang - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Medical science has witnessed significant progress in the development of hemostatic
materials, which save lives by supporting natural hemostatic ability. However, for the …

Thrombin immobilized polydopamine–diatom biosilica for effective hemorrhage control

Y Mu, Y Fu, J Li, K Shao, J Pang, C Su, Y Cai… - Biomaterials …, 2021 - pubs.rsc.org
In this study, an efficient composite hemostatic material (DA-diatom-T) was prepared, using
a polydopamine layer as a linker to immobilize thrombin on the surface of diatom biosilica …

[HTML][HTML] Platelet dysfunction after trauma: From mechanisms to targeted treatment

PH Sloos, P Vulliamy, C van't Veer, AS Gupta… - Transfusion, 2022 - ncbi.nlm.nih.gov
Trauma-induced bleeding is a leading cause of preventable mortality worldwide. 1–3
Severely injured bleeding trauma patients frequently present with trauma-induced …

Frozen platelets—development and future directions

K Kelly, JA Cancelas, ZM Szczepiorkowski… - Transfusion Medicine …, 2020 - Elsevier
Storage requirements and outdating of platelets represent a continued challenge for blood
banks. These hurdles are confounded for rural area hospitals or in military deployments …

Horizontal MicroRNA transfer by platelets–evidence and implications

M Mussbacher, A Pirabe, L Brunnthaler… - Frontiers in …, 2021 - frontiersin.org
For decades, platelets have been known for their central role in hemostasis and their ability
to release bioactive molecules, allowing inter-platelet communication and crosstalk with the …

Delivery of mRNA to platelets using lipid nanoparticles

S Novakowski, K Jiang, G Prakash, C Kastrup - Scientific reports, 2019 - nature.com
Platelets are natural delivery vehicles within the blood, carrying and releasing their contents
at sites of vasculature damage. Investigating the biology of platelets, and modifying them for …