Antibody discovery has become increasingly important in almost all areas of modern
medicine. Different antibody discovery approaches exist, but one that has gained increasing …

Antibodies as ideal therapeutic and diagnostic molecules are among the top-selling drugs
providing considerable efficacy in disease treatment, especially in cancer therapy …

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower
cost. Here, we describe the first fully synthetic phage display library of humanized llama …

Correct elucidation of physiological and pathological processes mediated by extracellular
vesicles (EV) is highly dependent on the reliability of the method used for their purification …

Abstract Background Nanobodies (Nbs) have proved their great value as therapeutic
molecules and clinical diagnostic tools. Although the routine procedure to obtain Nbs is to …

Evolution of nanomedicine is the re-design of synthetic and biological carriers to implement
novel theranostic platforms. In recent years, bacteriophage research favors this process …

Intracellular antibodies (intrabodies) are recombinant antibody fragments that bind to target
proteins expressed inside of the same living cell producing the antibodies. The molecules …

The book provides a comprehensive view of the impact and promise of phage display in
drug discovery and biotechnology. Building on the success of its previous edition, the book …

Antibodies are attractive therapeutic candidates due to their ability to bind cognate antigens
with high affinity and specificity. Still, the underlying molecular rules governing the antibody …

Single domain antibodies (sdAbs) from camels or sharks comprise only the variable heavy
chain domain. Human sdAbs comprise the variable domain of the heavy chain (VH) or light …