Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …

Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …

The transcription factor nuclear factor erythroid-derived 2-like 2 (NRF2) participates in the
activation of the antioxidant cytoprotective pathway and other important physiological …

Control of protein levels by nucleic-acid-based technologies has proven to be a useful
research tool but lacks the advantages of small molecules with respect to cell permeability …

Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved
serine/threonine protein kinase encoded in mammals by two genes that generate two …

Hsp90 is a major molecular chaperone that is expressed abundantly and plays a pivotal role
in assisting correct folding and functionality of its client proteins in cells. The Hsp90 client …

Abstract Glycogen synthase kinase-3 (GSK-3) is an unusual protein-serine kinase in that it is
primarily regulated by inhibition and lies downstream of multiple cell signaling pathways …

Summary The Disrupted in Schizophrenia 1 (DISC1) gene is disrupted by a balanced
chromosomal translocation (1; 11)(q42; q14. 3) in a Scottish family with a high incidence of …

The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is
crucial for proper execution of the DNA damage-induced stress response. While stalling of …

Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has
become an important strategy for treating neurodegenerative and psychiatric disorders. The …