In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Fungal biofilms are an escalating clinical problem associated with significant rates of
mortality. Candida albicans is the most notorious of all fungal biofilm formers. However, non …

The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …

The resistance of Candida albicans to many stresses is dependent on the stress-activated
protein kinase (SAPK) Hog1. Hence we have explored the role of Hog1 in the regulation of …

To establish an infection, the pathogen Candida albicans must assimilate carbon and grow
in its mammalian host. This fungus assimilates six‐carbon compounds via the glycolytic …

The production of reactive oxygen species (ROS) is a ubiquitous defense response in
plants. Adapted pathogens evolved mechanisms to counteract the deleterious effects of host …

The human commensal fungus Candida albicans can cause not only superficial infections,
but also life-threatening disease in immunocompromised individuals. C. albicans can grow …