Fluorine‐containing compounds have been widely applied on pharmaceuticals,
agrochemicals, and materials. The synthetic methodology for the introduction of fluorine into …

Selective C− F bond functionalization of perfluoalkyl units has huge potential towards
accessing functionalized organofluorinated compounds, but remains challenging due to the …

An unprecedented Pd‐catalyzed fluorinative bifunctionalization of aziridines and azetidines
was successfully developed via regioselective C− C and C− F bond cleavage of gem …

Fluorinated organoboranes serve as versatile synthetic precursors for the preparation of
value‐added fluorinated organic compounds. Recent progress has been mainly focused on …

The introduction of fluorine‐containing groups into organic molecules can significantly affect
their physical and chemical properties and has long been used as an effective strategy for …

Conventional approaches for Pd‐catalyzed ring‐opening cross‐couplings of gem‐
difluorocyclopropanes with nucleophiles predominantly deliver the β‐fluoroalkene scaffolds …

We report a NiH‐catalyzed migratory defluorinative coupling between two electronically
differentiated olefins. A broad range of unactivated donor olefins can be joined directly to …

Direct synthesis of gem‐difluorinated carbocyclic molecules represents a longstanding
challenge in organic chemistry. Herein, a Rh‐catalyzed [3+ 2] cycloaddition reaction …

Stereo‐and enantioselective cross‐electrophile coupling involving C− F bond activation is
reported. Treatment of gem‐difluoroalkenes with racemic benzyl electrophiles in the …

The activation and functionalization of C− F bonds in various fluoroorganics were found to
be a daunting task owing to their innate inertness. Harnessing the C− F bonds will alleviate …