2023 ESC guidelines for the management of acute coronary syndromes: developed by the task force on the management of acute coronary syndromes of the …

RA Byrne, X Rossello, JJ Coughlan… - … Heart Journal: Acute …, 2024 - academic.oup.com
2023 ESC Guidelines for the management of acute coronary syndromes Page 1 2023 ESC
Guidelines for the management of acute coronary syndromes Developed by the task force on …

Risk of major adverse cardiovascular events of CYP2C19 loss-of-function genotype guided prasugrel/ticagrelor vs clopidogrel therapy for acute coronary syndrome …

M Biswas, MSK Kali, TK Biswas, B Ibrahim - Platelets, 2021 - Taylor & Francis
The most effective antiplatelet treatments for acute coronary syndrome (ACS) patients
carrying CYP2C19 loss-of-function (LoF) alleles undergoing percutaneous coronary …

Ticagrelor versus clopidogrel in patients with STEMI treated with fibrinolysis: TREAT trial

O Berwanger, RD Lopes, DDF Moia… - Journal of the American …, 2019 - jacc.org
Background: The efficacy of ticagrelor in the long-term post–ST-segment elevation
myocardial infarction (STEMI) treated with fibrinolytic therapy remains uncertain. Objectives …

Ideal P2Y12 inhibitor in acute coronary syndrome: a review and current status

A Pradhan, A Tiwari, G Caminiti, C Salimei… - International Journal of …, 2022 - mdpi.com
Dual antiplatelet therapy (DAPT) has remained the cornerstone for management of acute
coronary syndrome (ACS) over the years. Clopidogrel has been the quintessential P2Y12 …

Systematic review with meta‐analysis: the risk of gastrointestinal bleeding in patients taking third‐generation P2Y12 inhibitors compared with clopidogrel

CG Guo, L Chen, EW Chan, KS Cheung… - Alimentary …, 2019 - Wiley Online Library
Background Ticagrelor and prasugrel are third‐generation oral P2Y12 receptor antagonists
with rapid onset and pronounced platelet inhibition. However, higher overall bleeding rates …

The risk of dyspnea in patients treated with third-generation P2Y12 inhibitors compared with clopidogrel: a meta-analysis of randomized controlled trials

N Zhang, W Xu, O Li, B Zhang - BMC cardiovascular disorders, 2020 - Springer
Background Ticagrelor and prasugrel are two third-generation oral P2Y 12 inhibitors which
are more commonly used in clinical practice. However, dyspnea has been consecutively …

Efficacy and safety of low dose ticagrelor in patients with acute coronary syndrome: a systematic review and meta-analysis

Q Chen, Y Zhang, Z Wang, S Wang… - Postgraduate …, 2020 - academic.oup.com
Our aim was to examine clinical trials, provide guidance to practitioners and estimate the
efficacy and safety of two agents by comparing low dose ticagrelor with standard dose …

Safety of Clopidogrel vs. Ticagrelor in Dual Antiplatelet Therapy Regimens for High-Bleeding Risk Acute Coronary Syndrome Patients: A Comprehensive Meta …

AR Khalid, F Ahmad, MAB Naeem, S Ahmed… - High Blood Pressure & …, 2024 - Springer
Introduction Patients of acute coronary syndrome (ACS) at a high-bleeding risk (HBR) often
require dual antiplatelet therapy (DAPT) to reduce the risk of recurrent cardiovascular …

Use of ticagrelor alongside fibrinolytic therapy in patients with ST‐segment elevation myocardial infarction: practical perspectives based on data from the TREAT study

O Berwanger, M Abdelhamid, T Alexander… - Clinical …, 2018 - Wiley Online Library
Primary percutaneous coronary intervention (PCI) is the preferred reperfusion method in
patients with ST‐segment elevation myocardial infarction (STEMI). In patients with STEMI …

P2Y12 inhibitors for the treatment of acute coronary syndrome patients undergoing percutaneous coronary intervention: current understanding and outcomes

D Alexopoulos, C Varlamos, A Mpahara… - Expert Review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: Inhibition of P2Y12 platelet receptors consists a crucial target of
pharmacologic treatment in acute coronary syndrome patients. Several controversial issues …