Introduction: X-ray crystallography provides the majority of our structural biological
knowledge at a molecular level and, in terms of pharmaceutical design, is a valuable tool to …

The Machine Recognition of Crystallization Outcomes (MARCO) initiative has assembled
roughly half a million annotated images of macromolecular crystallization experiments from …

Diffraction-based structural methods contribute a large fraction of the biomolecular structural
models available, providing a critical understanding of macromolecular architecture. These …

Observations of crystallization experiments are classified as specific outcomes and
integrated through a phase diagram to visualize solubility and thereby direct subsequent …

Crystallization is a key step in macromolecular structure determination by crystallography.
While a robust theoretical treatment of the process is available, due to the complexity of the …

We have developed an image-analysis and classification system for automatically scoring
images from high-throughput protein crystallization trials. Image analysis for this system is …

Obtaining a protein's 3D structure is crucial to the understanding of its functions and
interactions with other proteins. It is critical to accelerate the protein crystallization process …

This article begins by highlighting some of the ground-based studies emanating from
NASA's Microgravity Protein Crystal Growth (PCG) program. This is followed by a more …

Structural biology has contributed tremendous knowledge to the understanding of life on the
molecular scale. The Protein Data Bank, a depository of this structural knowledge, currently …

The various interplaying variables of tumor growth remain key questions in cancer research,
in particular what makes such a growth malignant and what are possible therapies to stop …