Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

As an essential component of innate immunity, macrophages have multiple functions in both
inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are …

Cancers develop in complex tissue environments, which they depend on for sustained
growth, invasion and metastasis. Unlike tumor cells, stromal cell types within the tumor …

Macrophages (Mf) are a heterogeneous population of tissue-resident professional
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …

Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

BACKGROUND Data from studies conducted in rodent models have shown that decreased
adipose tissue (AT) oxygenation is involved in the pathogenesis of obesity-induced insulin …

Retinal ganglion cells (RGC s) are the sole projecting neurons of the retina and their axons
form the optic nerve. Here, we show that embryogenesis‐associated mouse RGC …

Chronic obstructive pulmonary disease (COPD) is characterized by lung inflammation that
persists after smoking cessation. This inflammation is heterogeneous but the key …

Tumor-associated macrophages (TAM) plasticity and diversity are both essential hallmarks
of the monocyte-macrophage lineage and the tumor-derived inflammation. TAM exemplify …

Cancer is one of the most common diseases afflicting people globally. New therapeutic
approaches are needed due to the complexity of cancer as a disease. Many current …