The influence of nanoparticle properties on oral bioavailability of drugs

Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

Clinical advances of siRNA-based nanotherapeutics for cancer treatment

D Hattab, AM Gazzali, A Bakhtiar - Pharmaceutics, 2021 - mdpi.com
Cancer is associated with single or multiple gene defects. Recently, much research has
focused on incorporating genetic materials as one of the means to treat various types of …

CircRNA inhibits DNA damage repair by interacting with host gene

X Xu, J Zhang, Y Tian, Y Gao, X Dong, W Chen… - Molecular cancer, 2020 - Springer
Abstract Background Deregulated circular RNAs (circRNAs) are associated with the
development of cancer and therapy resistance. However, functional research of circRNAs …

3rd ESO–ESMO international consensus guidelines for advanced breast cancer (ABC 3)

F Cardoso, A Costa, E Senkus, M Aapro, F André… - The Breast, 2017 - Elsevier
Author links open overlay panel F. Cardoso a, A. Costa bc, E. Senkus d, M. Aapro e, F.
André f, CH Barrios g, J. Bergh h, G. Bhattacharyya i, L. Biganzoli j, MJ Cardoso k, L. Carey l …

Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

X Duan, C Chan, W Han, N Guo… - Nature …, 2019 - nature.com
Nanoparticles can potentially stimulate tumour microenvironments to elicit antitumour
immunity. Herein, we demonstrate effective immunotherapy of colorectal cancer via systemic …

Tumor evolution as a therapeutic target

N Amirouchene-Angelozzi, C Swanton, A Bardelli - Cancer discovery, 2017 - AACR
Recent technological advances in the field of molecular diagnostics (including blood-based
tumor genotyping) allow the measurement of clonal evolution in patients with cancer, thus …

Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect

G Bocci, RS Kerbel - Nature Reviews Clinical Oncology, 2016 - nature.com
Metronomic chemotherapy describes the close, regular administration of chemotherapy
drugs at less-toxic doses over prolonged periods of time. In 2015, the results of randomized …

Supramolecular macrophage‐liposome marriage for cell‐hitchhiking delivery and immunotherapy of acute pneumonia and melanoma

C Gao, Q Cheng, J Li, J Chen, Q Wang… - Advanced Functional …, 2021 - Wiley Online Library
As many diseases are related to inflammation, the inflammatory tropism of immune cells may
bring cell‐hitchhikers directly to the disease tissues in a highly targeted manner. The current …

[HTML][HTML] Clinical validity of tumor-infiltrating lymphocytes analysis in patients with triple-negative breast cancer

G Pruneri, A Vingiani, V Bagnardi, N Rotmensz… - Annals of oncology, 2016 - Elsevier
Background Although tumor-infiltrating lymphocytes (TILs) have been associated with a
favorable prognosis in triple-negative breast cancer (TNBC) patients, this marker is not …

Hydrogen-bonded tannic acid-based anticancer nanoparticle for enhancement of oral chemotherapy

Z Le, Y Chen, H Han, H Tian, P Zhao… - … applied materials & …, 2018 - ACS Publications
Oral chemotherapy has been emerging as a hopeful therapeutic regimen for the treatment of
various cancers because of its high safety and convenience, lower costs, and high patient …