The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily
NM Sherwood, SL Krueckl, JE McRory - Endocrine reviews, 2000 - academic.oup.com
The pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily
includes nine hormones in humans that are related by structure, distribution (especially the …
includes nine hormones in humans that are related by structure, distribution (especially the …
Renewal of photoreceptor outer segments and their phagocytosis by theretinal pigment epithelium
J Nguyen-Legros, D Hicks - International review of cytology, 2000 - Elsevier
The discovery of disc protein renewal in rod outer segments, in 1960s, was followed by the
observation that old discs were ingested by the retinal pigment epithelium. This process …
observation that old discs were ingested by the retinal pigment epithelium. This process …
N‐terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants
Dautzenberg, Mevenkamp, Wille… - Journal of …, 1999 - Wiley Online Library
Three full‐length cDNAs encoding functional splice variants of the pituitary adenylate
cyclase‐activating polypeptide (PACAP) type 1 receptor (PAC1) were isolated from Y‐79 …
cyclase‐activating polypeptide (PACAP) type 1 receptor (PAC1) were isolated from Y‐79 …
Distribution of the VPAC2 Receptor in Peripheral Tissues of the Mouse
AJ Harmar, WJ Sheward, CF Morrison, B Waser… - …, 2004 - academic.oup.com
The neuropeptide vasoactive intestinal peptide (VIP) exerts its actions through two
structurally related G protein-coupled receptors (VPAC1 and VPAC2). Pituitary adenylate …
structurally related G protein-coupled receptors (VPAC1 and VPAC2). Pituitary adenylate …
Pituitary adenylate cyclase activating polypeptide in the retina: focus on the retinoprotective effects
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neurotrophic and
neuroprotective peptide that has been shown to exert protective effects against different …
neuroprotective peptide that has been shown to exert protective effects against different …
[HTML][HTML] Pleiotropic and retinoprotective functions of PACAP
S Shioda, F Takenoya, N Wada, T Hirabayashi… - Anatomical science …, 2016 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 27-or 38-amino acid
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
Distribution of PACAP and PAC1 Receptor in the Human Eye
E Patko, E Szabo, D Toth, T Tornoczky… - Journal of Molecular …, 2022 - Springer
Pituitary adenylate cyclase–activating polypeptide (PACAP) is a neuropeptide with
widespread distribution and diverse biological functions. Several studies show that PACAP …
widespread distribution and diverse biological functions. Several studies show that PACAP …
The neuroprotective effects of PACAP in monosodium glutamate-induced retinal lesion involve inhibition of proapoptotic signaling pathways
B Rácz, F Gallyas Jr, P Kiss, G Tóth, O Hegyi, B Gasz… - Regulatory peptides, 2006 - Elsevier
Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors are present in
the retina and exert several distinct functions. PACAP has well-known neuroprotective …
the retina and exert several distinct functions. PACAP has well-known neuroprotective …
Pituitary adenylyl cyclase-activating polypeptide prevents induced cell death in retinal tissue through activation of cyclic AMP-dependent protein kinase
Multiple neuroactive substances are secreted by neurons and/or glial cells and modulate the
sensitivity to cell death. In the developing retina, it has been shown that increased …
sensitivity to cell death. In the developing retina, it has been shown that increased …
Attenuation by PACAP of glutamate-induced neurotoxicity in cultured retinal neurons
K Shoge, HK Mishima, T Saitoh, K Ishihara, Y Tamura… - Brain research, 1999 - Elsevier
The effects of pituitary adenylate cyclase activating polypeptides (PACAPs: PACAP27,
PACAP38) on glutamate-induced neurotoxicity were examined using cultured retinal …
PACAP38) on glutamate-induced neurotoxicity were examined using cultured retinal …