Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination

CJ Chaccour, KC Kobylinski, Q Bassat, T Bousema… - Malaria journal, 2013 - Springer
Background The heterogeneity of malaria transmission makes widespread elimination a
difficult goal to achieve. Most of the current vector control measures insufficiently target …

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety

C Chaccour, F Hammann, NR Rabinovich - Malaria Journal, 2017 - Springer
Ivermectin is an endectocide that has been used broadly in single dose community
campaigns for the control of onchocerciasis and lymphatic filariasis for more than 30 years …

Novel control strategies for mosquito-borne diseases

RT Jones, TH Ant, MM Cameron… - … Transactions of the …, 2021 - royalsocietypublishing.org
Mosquito-borne diseases are an increasing global health challenge, threatening over 40%
of the world's population. Despite major advances in malaria control since 2000, recent …

[HTML][HTML] Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial

BD Foy, H Alout, JA Seaman, S Rao, T Magalhaes… - The Lancet, 2019 - thelancet.com
Background Ivermectin is widely used in mass drug administrations for controlling neglected
parasitic diseases, and can be lethal to malaria vectors that bite treated humans. Therefore …

Oral, ultra–long-lasting drug delivery: application toward malaria elimination goals

AM Bellinger, M Jafari, TM Grant, S Zhang… - Science translational …, 2016 - science.org
Efforts at elimination of scourges, such as malaria, are limited by the logistic challenges of
reaching large rural populations and ensuring patient adherence to adequate …

[HTML][HTML] Antiparasitic activity of ivermectin: Four decades of research into a “wonder drug”

M Sulik, M Antoszczak, A Huczyński… - European Journal of …, 2023 - Elsevier
Parasitic diseases still pose a serious threat to human and animal health, particularly for
millions of people and their livelihoods in low-income countries. Therefore, research into the …

[HTML][HTML] A roadmap for the development of ivermectin as a complementary malaria vector control tool

TI Roadmappers - The American journal of tropical medicine and …, 2020 - ncbi.nlm.nih.gov
In the context of stalling progress against malaria, resistance of mosquitoes to insecticides,
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …

Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers

J Muñoz, MR Ballester, RM Antonijoan… - PLoS neglected …, 2018 - journals.plos.org
Ivermectin is a pivotal drug for the control of onchocerciasis and lymphatic filariasis, which is
increasingly identified as a useful drug for the control of other Neglected Tropical Diseases …

The potential impact of adding ivermectin to a mass treatment intervention to reduce malaria transmission: a modelling study

HC Slater, PGT Walker, T Bousema… - The Journal of …, 2014 - academic.oup.com
Background Ivermectin (IVM), used alongside mass treatment strategies with an artemisinin
combination therapy, has been suggested as a possible tool for reducing malaria …

Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments

H Alout, BJ Krajacich, JI Meyers, ND Grubaugh… - Malaria journal, 2014 - Springer
Background Mass drug administration (MDA) of ivermectin to humans for control and
elimination of filarial parasites can kill biting malaria vectors and lead to Plasmodium …