Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination
Background The heterogeneity of malaria transmission makes widespread elimination a
difficult goal to achieve. Most of the current vector control measures insufficiently target …
difficult goal to achieve. Most of the current vector control measures insufficiently target …
Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety
Ivermectin is an endectocide that has been used broadly in single dose community
campaigns for the control of onchocerciasis and lymphatic filariasis for more than 30 years …
campaigns for the control of onchocerciasis and lymphatic filariasis for more than 30 years …
Novel control strategies for mosquito-borne diseases
RT Jones, TH Ant, MM Cameron… - … Transactions of the …, 2021 - royalsocietypublishing.org
Mosquito-borne diseases are an increasing global health challenge, threatening over 40%
of the world's population. Despite major advances in malaria control since 2000, recent …
of the world's population. Despite major advances in malaria control since 2000, recent …
[HTML][HTML] Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial
Background Ivermectin is widely used in mass drug administrations for controlling neglected
parasitic diseases, and can be lethal to malaria vectors that bite treated humans. Therefore …
parasitic diseases, and can be lethal to malaria vectors that bite treated humans. Therefore …
Oral, ultra–long-lasting drug delivery: application toward malaria elimination goals
Efforts at elimination of scourges, such as malaria, are limited by the logistic challenges of
reaching large rural populations and ensuring patient adherence to adequate …
reaching large rural populations and ensuring patient adherence to adequate …
[HTML][HTML] Antiparasitic activity of ivermectin: Four decades of research into a “wonder drug”
M Sulik, M Antoszczak, A Huczyński… - European Journal of …, 2023 - Elsevier
Parasitic diseases still pose a serious threat to human and animal health, particularly for
millions of people and their livelihoods in low-income countries. Therefore, research into the …
millions of people and their livelihoods in low-income countries. Therefore, research into the …
[HTML][HTML] A roadmap for the development of ivermectin as a complementary malaria vector control tool
TI Roadmappers - The American journal of tropical medicine and …, 2020 - ncbi.nlm.nih.gov
In the context of stalling progress against malaria, resistance of mosquitoes to insecticides,
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …
and residual transmission, mass drug administration (MDA) of ivermectin, an endectocide …
Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers
J Muñoz, MR Ballester, RM Antonijoan… - PLoS neglected …, 2018 - journals.plos.org
Ivermectin is a pivotal drug for the control of onchocerciasis and lymphatic filariasis, which is
increasingly identified as a useful drug for the control of other Neglected Tropical Diseases …
increasingly identified as a useful drug for the control of other Neglected Tropical Diseases …
The potential impact of adding ivermectin to a mass treatment intervention to reduce malaria transmission: a modelling study
Background Ivermectin (IVM), used alongside mass treatment strategies with an artemisinin
combination therapy, has been suggested as a possible tool for reducing malaria …
combination therapy, has been suggested as a possible tool for reducing malaria …
Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments
Background Mass drug administration (MDA) of ivermectin to humans for control and
elimination of filarial parasites can kill biting malaria vectors and lead to Plasmodium …
elimination of filarial parasites can kill biting malaria vectors and lead to Plasmodium …