Myeloid cells are pivotal within the immunosuppressive tumour microenvironment. The
accumulation of tumour-modified myeloid cells derived from monocytes or neutrophils …

TAM (TYRO3, AXL, and MERTK) protein tyrosine kinase membrane receptors and their
vitamin K-dependent ligands GAS6 and protein S (PROS) are well-known players in tumor …

Microglia, the resident macrophages of the central nervous system (CNS), play a critical role
in CNS homeostasis and neuroinflammation. Pexidartinib (PLX3397), a colony-stimulating …

Tumor-associated macrophages (TAMs) are closely associated with poor multiple myeloma
(MM) prognosis. Therefore, in-depth understanding of the mechanism by which TAM …

Neutrophils with immunoregulatory properties, also referred to as type-2 neutrophils (N2),
myeloid-derived suppressor cells (MDSCs), or tumor-associated neutrophils (TANs) …

Salivary gland (SG) hypofunction is a common post-radiotherapy complication. Besides the
parenchymal damage after irradiation (IR), there are also effects on mesenchymal stem cells …

Introduction The current study focuses on understanding the functional role of different
subsets of endoneurial macrophages in autoimmune polyneuropathies (AP) and traumatic …

Kupffer cells are maintained via self-renewal in specific microenvironmental niches,
primarily the liver sinusoidal endothelial cells (LSECs). In this study, we propagated tissue …

Kupffer cells are pivotal in initiating hepatocyte proliferation and establishing connections
between different cell types during liver regeneration following partial hepatectomy. As …

The liver is the only organ that can regenerate and regain its original tissue-to-body weight
ratio within a short period of time after tissue loss. Insufficient liver regeneration in patients …