The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis

Y Lee, J Ni, J Beretov, VC Wasinger, P Graham, Y Li - Molecular cancer, 2023 - Springer
Current clinical tools for breast cancer (BC) diagnosis are insufficient but liquid biopsy of
different bodily fluids has recently emerged as a minimally invasive strategy that provides a …

Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Liquid biopsies in cancer diagnosis, monitoring, and prognosis

G De Rubis, SR Krishnan, M Bebawy - Trends in pharmacological sciences, 2019 - cell.com
Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Extracellular vesicle quantification and characterization: common methods and emerging approaches

TA Hartjes, S Mytnyk, GW Jenster, V van Steijn… - Bioengineering, 2019 - mdpi.com
Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …

[HTML][HTML] The biology, function, and applications of exosomes in cancer

J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …

Single-exosome-counting immunoassays for cancer diagnostics

C Liu, X Xu, B Li, B Situ, W Pan, Y Hu, T An, S Yao… - Nano …, 2018 - ACS Publications
Exosomes shed by tumor cells have been recognized as promising biomarkers for cancer
diagnostics due to their unique composition and functions. Quantification of low …

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping

S Rontogianni, E Synadaki, B Li, MC Liefaard… - Communications …, 2019 - nature.com
Extracellular vesicles (EVs) are a potential source of disease-associated biomarkers for
diagnosis. In breast cancer, comprehensive analyses of EVs could yield robust and reliable …