Gut microbiota modulation of chemotherapy efficacy and toxicity

JL Alexander, ID Wilson, J Teare, JR Marchesi… - Nature reviews …, 2017 - nature.com
Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

RV Lalla, J Bowen, A Barasch, L Elting, J Epstein… - Cancer, 2014 - Wiley Online Library
BACKGROUND Mucositis is a highly significant, and sometimes dose‐limiting, toxicity of
cancer therapy. The goal of this systematic review was to update the Multinational …

Systematic review: the role of the gut microbiota in chemotherapy‐or radiation‐induced gastrointestinal mucositis–current evidence and potential clinical applications

Y Touchefeu, E Montassier, K Nieman… - Alimentary …, 2014 - Wiley Online Library
Background Gastrointestinal mucositis is defined as inflammation and/or ulcers of the
gastrointestinal tract occurring as a complication of chemotherapy and radiation therapy …

Chemotherapy-induced oral mucositis is associated with detrimental bacterial dysbiosis

BY Hong, T Sobue, L Choquette, AK Dupuy… - Microbiome, 2019 - Springer
Background Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity,
is a clinically significant yet incompletely understood complication of cancer chemotherapy …

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

S Elad, KKF Cheng, RV Lalla, N Yarom, C Hong… - Cancer, 2020 - Wiley Online Library
Background Mucositis is a significant toxicity of cancer therapy with numerous systemic
sequelae. The goal of this systematic review was to update the Multinational Association of …

Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective

M Tomblyn, T Chiller, H Einsele, R Gress… - Bone marrow …, 2009 - nature.com
Guidelines for preventing infectious complications among hematopoietic cell transplant
recipients: a global perspective | Bone Marrow Transplantation Skip to main content Thank you …

ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs–threshold doses for tissue reactions in a …

FA Stewart, AV Akleyev, M Hauer-Jensen, JH Hendry… - Annals of the ICRP, 2012 - Elsevier
This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Mucositis: pathobiology and management

A Villa, ST Sonis - Current opinion in oncology, 2015 - journals.lww.com
Oral mucositis is a common complication of cancer treatment that may negatively impact the
patient's cancer treatment outcome. Despite its frequency and consequences, the lack of …

Management of oral and gastrointestinal mucosal injury: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up

DE Peterson, CB Boers-Doets… - Annals of …, 2015 - annalsofoncology.org
Oral and gastrointestinal mucositis caused by high-dose chemotherapy and/or radiation
continues to be an important clinical problem. Fortunately, there have been strategic …

Glutamine for amelioration of radiation and chemotherapy associated mucositis during cancer therapy

PM Anderson, RV Lalla - Nutrients, 2020 - mdpi.com
Glutamine is a major dietary amino acid that is both a fuel and nitrogen donor for healing
tissues damaged by chemotherapy and radiation. Evidence supports the benefit of oral …