Physical and digital phantoms for 2D and 3D x-ray breast imaging: Review on the state-of-the-art and future prospects

A Sarno, C Valero, RM Tucciariello, N Dukov… - Radiation Physics and …, 2023 - Elsevier
Breast phantoms are a fundamental asset both in routine quality assurance programs and
for comparing scanner performance in 2D and 3D x-ray breast imaging. They also play an …

Dataset of patient‐derived digital breast phantoms for in silico studies in breast computed tomography, digital breast tomosynthesis, and digital mammography

A Sarno, G Mettivier, F di Franco, A Varallo… - Medical …, 2021 - Wiley Online Library
Purpose To present a dataset of computational digital breast phantoms derived from high‐
resolution three‐dimensional (3D) clinical breast images for the use in virtual clinical trials in …

GEANT4 Monte Carlo simulations for virtual clinical trials in breast X-ray imaging: Proof of concept

F di Franco, A Sarno, G Mettivier, AM Hernandez… - Physica Medica, 2020 - Elsevier
Virtual clinical trials (VCT) are in-silico reproductions of medical examinations, which adopt
digital models of patients and simulated devices. They are intended to produce clinically …

Monte Carlo methods for medical imaging research

H Lee - Biomedical Engineering Letters, 2024 - Springer
In radiation-based medical imaging research, computational modeling methods are used to
design and validate imaging systems and post-processing algorithms. Monte Carlo methods …

Image simulation and realism evaluation for mammography and tomosynthesis based on the detailed breast phantom

J Wang, Y Liu, A Hu, S Wei, T Wu, J Li, R Qiu - Radiation Physics and …, 2023 - Elsevier
The virtual image system is a key component of virtual clinical trials (VCTs) which can be
utilized to evaluate and improve medical imaging devices. The main limitation of VCTs in the …

Normalized glandular dose coefficients for digital breast tomosynthesis systems with a homogeneous breast model

A Sarno, RM Tucciariello, G Mettivier… - Physics in Medicine …, 2021 - iopscience.iop.org
This work aims at calculating and releasing tabulated values of dose conversion coefficients,
DgN DBT, for mean glandular dose (MGD) estimates in digital breast tomosynthesis (DBT) …

A model for a linear a-Se detector in simulated x-ray breast imaging with Monte Carlo software

A Sarno, RM Tucciariello, ME Fantacci… - … on Radiation and …, 2024 - ieeexplore.ieee.org
In-silico clinical trials with digital patient models and simulated devices are an alternative to
expensive and long clinical trials on patient population for testing X-ray breast imaging …

Application of 3D printed anthropomorphic phantoms for research and educational purposes in digital radiology

K Bliznakova, N Okkalidis, N Dukov… - … Conference on e …, 2020 - ieeexplore.ieee.org
Three-dimensional (3D) printing is nowadays a necessary tool in many medical
applications. In radiation medicine, this technology is exploited to manufacture …

Simulated sensor characterization for virtual clinical trials in mammography and digital breast tomosynthesis

A Sarno, RM Tucciariello - Journal of Instrumentation, 2022 - iopscience.iop.org
Virtual clinical trials in X-ray breast imaging permit to compare different technical solutions
and imaging modalities at reduced costs, involved personnel, reduced times and reduced …

Empirical detector model for simulated breast exams with a dedicated breast CT scanner

A Sarno, G Mettivier, K Michielsen… - … Workshop on Breast …, 2022 - spiedigitallibrary.org
This work proposes an empirical model for tuning spatial resolution and noise in simulated
images in virtual clinical trials in x-ray breast imaging. In extending previous studies …