Construction of a bivalent vaccine candidate against HAdV4/HAdV7 based on capsid-display strategy via Red-homologous recombination and counter-selection …

P Wang, Y Shao, X Yang, W Zhang, J Zhou… - Biosafety and …, 2024 - mednexus.org
Human adenoviruses (HAdVs) are major respiratory pathogens. Specifically, human
adenovirus type 4 (HAdV4) and human adenovirus type 7 (HAdV7) are known for causing …

High genetic stability of co-circulating human adenovirus type 31 lineages over 59 years

J Götting, C Baier, V Panagiota… - Virus …, 2022 - academic.oup.com
Type 31 of human adenovirus species A (HAdV-A31) is a significant pathogen primarily
associated with diarrhoea in children but also with life-threatening disseminated disease in …

Human adenovirus type 4 (HAdV-4) associated acute respiratory tract infection in children & genetic characteristics of HAdV-4 in China: a prospective multicenter …

J Wang, Q Feng, Y Duan, J Ai, Y Zhu, R Wang… - BMC Infectious …, 2024 - Springer
Abstract Background Human adenovirus (HAdV) is an important pathogen causing acute
respiratory infection (ARI) in children. Many countries, including China, have experienced …

Molecular characterization of human adenoviruses associated with pediatric respiratory infections in Karachi, Pakistan

K Mahmood, W Ahmed, S Farooq, G Habib… - BMC Infectious …, 2024 - Springer
Human adenoviruses (HAdVs) are a diverse group of viruses associated with respiratory
infections in humans worldwide. However, there is a lack of research on the genetic diversity …

[HTML][HTML] Phylogenetic characterization of rhinovirus and adenovirus in hospitalized children aged≤ 18 years with severe acute respiratory infection in Iran

S Abbasi, NZ Shafiei-Jandaghi, A Shadab… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Materials and Methods: To detect these two viruses, a conventional nested RT-PCR
(Reverse transcription-polymerase chain reaction) assay was performed on 264 throat …

A bivalent live-attenuated vaccine candidate elicits protective immunity against human adenovirus types 4 and 7

J Guo, Y Zhang, Y Zhang, C Zhang, C Zhu… - Emerging Microbes & …, 2021 - Taylor & Francis
ABSTRACT Human adenovirus types 4 (HAdV4) and 7 (HAdV7) often lead to severe
respiratory diseases and occur epidemically in children, adults, immune deficiency patients …

Adenoviruses

Q Zhang - Molecular Medical Microbiology, 2024 - Elsevier
Adenoviruses are nonenveloped DNA viruses with a broad range of vertebrate hosts.
Adenoviruses cause significant morbidity in humans, from mild respiratory infections to …

Gastrointestinal viruses and beyond: antiviral development and molecular epidemiology

G Yan - 2023 - unsworks.unsw.edu.au
The risk of viral epidemics from emerging and re-emerging viruses has never been greater,
as exemplified by the current coronavirus pandemic. Changing climates, poor land use …

Molecular Typing of Human Adenovirus Infection among Hospitalized Patients with Respiratory Tract Infections in Guangzhou, China

X Wang, D Wang, S Umar, S Qin, Q Lin, GC Gray, Y Liu - 2021 - researchsquare.com
Background Human Adenoviruses (HAdVs) cause a wide array of illnesses in all age
groups. They particularly cause frequent morbidity among children. In China, human …

The failure to meet GMP on completely eliminating replication-competent adenoviruses in vaccines using the chimpanzees Adv will have disastrous consequences …

S Chakraborty - osf.io
Abstract Chimpanzee adenovirus (Y25, Accid: JN254802. 1) is being used in the ChAdOx1-
nCOV (Covishield) vaccine [1] because it has low human seroprevalence [2]. Closest to …