Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …

Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

Introduction Acute kidney injury (AKI) can evolve quickly and clinical measures of function
often fail to detect AKI at a time when interventions are likely to provide benefit. Identifying …

Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Cellular senescence is an important mechanism for preventing the proliferation of potential
cancer cells. Recently, however, it has become apparent that this process entails more than …

Cellular senescence suppresses cancer by forcing potentially oncogenic cells into a
permanent cell cycle arrest. Senescent cells also secrete growth factors, proteases, and …

Cellular senescence suppresses cancer by stably arresting the proliferation of damaged
cells. Paradoxically, senescent cells also secrete factors that alter tissue microenvironments …

Background Difficulties in prediction and early identification of (acute kidney injury) AKI have
hindered the ability to develop preventive and therapeutic measures for this syndrome. We …

A major constraint on the evolution of large body sizes in animals is an increased risk of
developing cancer. There is no correlation, however, between body size and cancer risk …

The main goal when treating malignancies with radiation therapy is to deprive tumor cells of
their reproductive potential. One approach to achieve this is by inducing tumor cell …