Diabetes, a silent killer, is one of the most widely prevalent conditions of the present time.
According to the 2017 International Diabetes Federation (IDF) statistics, the global …

Prevention of type 2 diabetes (T2D) is a great challenge worldwide. The aim of this evidence
synthesis was to summarize the available evidence in order to update the European …

Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly
accumulated that insulin action in the brain produces multiple behavioral and metabolic …

Obesity and insulin resistance are associated with the development of type 2 diabetes. It is
well accepted that beta cell dysfunction is required for hyperglycaemia to occur. The …

Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by
glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10 …

OBJECTIVE: This article examines the foundation of β-cell failure in type 2 diabetes (T2D)
and suggests areas for future research on the underlying mechanisms that may lead to …

Type 2 diabetes mellitus (T2DM) is one of the major causes of premature morbidity and
mortality worldwide with the World Health Organization reporting that 1 in 10 adults …

Context The frequency of remission of type 2 diabetes achievable with lifestyle intervention
is unclear. Objective To examine the association of a long-term intensive weight-loss …

The aim of this paper is to provide a comprehensive review of the epidemiological evidence
linking type 2 diabetes mellitus and its related conditions, including obesity …

Obesity is a major public health problem worldwide, and it is associated with an increased
risk of developing type 2 diabetes. It is now commonly accepted that chronic inflammation …