Most methods for single-cell transcriptome sequencing amplify the termini of polyadenylated
transcripts, capturing only a small fraction of the total cellular transcriptome. This precludes …

Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

Synaptic plasticity mechanisms are usually discussed in terms of changes in synaptic
strength. The capacity of excitatory synapses to rapidly modify the membrane expression of …

Induced CREB activity is a hallmark of long-term memory, but the full repertoire of CREB
transcriptional targets required specifically for memory is not known in any system. To obtain …

A plastic nervous system requires the ability not only to acquire and store but also to forget.
Here, we report that musashi (msi-1) is necessary for time-dependent memory loss in C …

The neural cell adhesion molecule 1 (NCAM-1) has been implicated in several brain-related
biological processes, including neuronal migration, axonal branching, fasciculation, and …

The ability to efficiently store memories in the brain is a fundamental process and its
impairment is associated with multiple human mental disorders. Evidence indicates that long …

Neurological diseases are among the leading causes of disability and death worldwide and
remain difficult to treat. Tissue engineering offers avenues to test potential treatments; …

While it is thought that short-term memory arises from changes in protein dynamics that
increase the strength of synaptic signaling, many of the underlying fundamental molecular …

Abstract Sorting Nexin 27 (SNX27) is a brain-enriched endosome-associated cargo adaptor
that shapes excitatory control, being relevant for cognitive and reward processing, and for …