The integration of adaptive radiation therapy (ART), or modifying the treatment plan during
the treatment course, is becoming more widely available in clinical practice. ART offers …

Brachytherapy is a specific form of radiotherapy consisting of the precise placement of
radioactive sources directly into or next to the tumor. This technique is indicated for patients …

Background The concept of the use of MRI for image-guided adaptive brachytherapy
(IGABT) in locally advanced cervical cancer was introduced 20 years ago. Here, we report …

Purpose Improvements in magnetic resonance imaging (MRI), total mesorectal excision
(TME) surgery, and the use of (chemo) radiotherapy ([C] RT) have improved local control of …

Motion and uncertainty in radiotherapy is traditionally handled via margins. The clinical
target volume (CTV) is expanded to a larger planning target volume (PTV), which is …

Each year, more than half a million women are diagnosed with cervical cancer and the
disease results in over 300 000 deaths worldwide. High-risk subtypes of the human …

External beam radiotherapy and brachytherapy are major treatments in the management of
cervical cancer. For early-stage tumours with local risk factors, brachytherapy is a …

Cervical cancer represents a significant portion of the global cancer burden for women, with
low-and middle-income countries carrying the bulk of this burden. Additionally, underserved …

The key goal and main challenge of radiation therapy is the elimination of tumors without
any concurring damages of the surrounding healthy tissues and organs. Radiation doses …

Purpose This study investigated deep learning models for automatic segmentation to
support the development of daily online dose optimization strategies, eliminating the need …