Semi-solid extrusion 3D printing in drug delivery and biomedicine: Personalised solutions for healthcare challenges

I Seoane-Viaño, P Januskaite… - Journal of controlled …, 2021 - Elsevier
Abstract Three-dimensional (3D) printing is an innovative additive manufacturing
technology, capable of fabricating unique structures in a layer-by-layer manner. Semi-solid …

[HTML][HTML] Buccal films: A review of therapeutic opportunities, formulations & relevant evaluation approaches

L Shipp, F Liu, L Kerai-Varsani, TC Okwuosa - Journal of Controlled …, 2022 - Elsevier
The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

Automated therapy preparation of isoleucine formulations using 3D printing for the treatment of MSUD: First single-centre, prospective, crossover study in patients

A Goyanes, CM Madla, A Umerji, GD Piñeiro… - International Journal of …, 2019 - Elsevier
Maple syrup urine disease (MSUD) is a rare metabolic disorder with a worldwide prevalence
of 1 in every 185,000 live births. However, certain populations display a significant …

3D printing of medicines: engineering novel oral devices with unique design and drug release characteristics

A Goyanes, J Wang, A Buanz… - Molecular …, 2015 - ACS Publications
Three dimensional printing (3D printing) was used to fabricate novel oral drug delivery
devices with specialized design configurations. Each device was loaded with multiple …

Long-acting reversible contraception by effervescent microneedle patch

W Li, J Tang, RN Terry, S Li, A Brunie, RL Callahan… - Science …, 2019 - science.org
To increase access to long-acting contraception, we developed a reversible contraceptive
microneedle patch that is simple-to-administer, slowly releases contraceptive hormone …

Fused-filament 3D printing of drug products: Microstructure analysis and drug release characteristics of PVA-based caplets

A Goyanes, M Kobayashi, R Martínez-Pacheco… - International journal of …, 2016 - Elsevier
Abstract Fused deposition modeling (FDM) 3–Dimensional (3D) printing is becoming an
increasingly important technology in the pharmaceutical sciences, since it allows the …

Quality of FDM 3D printed medicines for pediatrics: considerations for formulation development, filament extrusion, printing process and printer design

J Quodbach, M Bogdahn, J Breitkreutz… - … Innovation & Regulatory …, 2021 - Springer
Abstract 3d printing is capable of providing dose individualization for pediatric medicines
and translating the precision medicine approach into practical application. In pediatrics …

Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms

FL Lopez, TB Ernest, C Tuleu… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Most conventional drug delivery systems are not acceptable for pediatric
patients as they differ in their developmental status and dosing requirements from other …

[HTML][HTML] Paediatric specific dosage forms: Patient and formulation considerations

D Khan, D Kirby, S Bryson, M Shah… - International journal of …, 2022 - Elsevier
The total number of paediatric formulations available only account for a small proportion of
the full therapeutic plethora required to effectively treat paediatrics and, therefore, the …

Innovations in chewable formulations: the novelty and applications of 3D printing in drug product design

L Rodríguez-Pombo, A Awad, AW Basit… - Pharmaceutics, 2022 - mdpi.com
Since their introduction, chewable dosage forms have gained traction due to their ability to
facilitate swallowing, especially in paediatric, geriatric and dysphagia patients. Their benefits …