Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network

L Lou, P Zhang, R Piao, Y Wang - Frontiers in cellular and infection …, 2019 - frontiersin.org
Salmonella species can infect a diverse range of birds, reptiles, and mammals, including
humans. The type III protein secretion system (T3SS) encoded by Salmonella pathogenicity …

Salmonellae interactions with host processes

DL LaRock, A Chaudhary, SI Miller - Nature Reviews Microbiology, 2015 - nature.com
Salmonellae invasion and intracellular replication within host cells result in a range of
diseases, including gastroenteritis, bacteraemia, enteric fever and focal infections. In recent …

Mechanisms of phagocytosis in macrophages

A Aderem, DM Underhill - Annual review of immunology, 1999 - annualreviews.org
▪ Abstract Phagocytosis of pathogens by macrophages initiates the innate immune
response, which in turn orchestrates the adaptive response. In order to discriminate between …

Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion

H Brüssow, C Canchaya… - … and molecular biology …, 2004 - Am Soc Microbiol
Comparative genomics demonstrated that the chromosomes from bacteria and their viruses
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …

Type III protein secretion systems in bacterial pathogens of animals and plants

CJ Hueck - Microbiology and molecular biology reviews, 1998 - Am Soc Microbiol
Various gram-negative animal and plant pathogens use a novel, sec-independent protein
secretion system as a basic virulence mechanism. It is becoming increasingly clear that …

Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

M Barthel, S Hapfelmeier… - Infection and …, 2003 - Am Soc Microbiol
Salmonella enterica subspecies 1 serovar Typhimurium is a principal cause of human
enterocolitis. For unknown reasons, in mice serovar Typhimurium does not provoke …

Typhoidal Salmonella: Distinctive virulence factors and pathogenesis

R Johnson, E Mylona, G Frankel - Cellular microbiology, 2018 - Wiley Online Library
Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

D Hersh, DM Monack, MR Smith… - Proceedings of the …, 1999 - National Acad Sciences
Recently, Salmonella spp. were shown to induce apoptosis in infected macrophages. The
mechanism responsible for this process is unknown. In this report, we establish that the Inv …

S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells

WD Hardt, LM Chen, KE Schuebel, XR Bustelo… - Cell, 1998 - cell.com
S. typhimurium stimulates signaling pathways leading to membrane ruffling, actin
cytoskeleton rearrangements, and nuclear responses. The stimulation requires a protein …

Bacteriophage control of bacterial virulence

PL Wagner, MK Waldor - Infection and immunity, 2002 - Am Soc Microbiol
In 1930, Felix d'Herelle wrote “... the actions and reactions are not solely between these two
beings, man and bacterium, for the bacteriophage also intervenes; a third living being and …