The protometabolic nature of prebiotic chemistry

N Nogal, M Sanz-Sánchez, S Vela-Gallego… - Chemical Society …, 2023 - pubs.rsc.org
The field of prebiotic chemistry has been dedicated over decades to finding abiotic routes
towards the molecular components of life. There is nowadays a handful of prebiotically …

Artificial Homeostasis Systems Based on Feedback Reaction Networks: Design Principles and Future Promises

VA Ranganath, I Maity - Angewandte Chemie International …, 2024 - Wiley Online Library
Feedback‐controlled chemical reaction networks (FCRNs) are indispensable for various
biological processes, such as cellular mechanisms, patterns, and signaling pathways …

Memory, switches, and an OR-port through bistability in chemically fueled crystals

F Schnitter, B Rieß, C Jandl, J Boekhoven - Nature Communications, 2022 - nature.com
The ability to store information in chemical reaction networks is essential for the complex
behavior we associate with life. In biology, cellular memory is regulated through …

Feedback and communication in active hydrogel spheres with pH fronts: facile approaches to grow soft hydrogel structures

I Maity, C Sharma, F Lossada… - Angewandte Chemie …, 2021 - Wiley Online Library
Compartmentalized reaction networks regulating signal processing, communication and
pattern formation are central to living systems. Towards achieving life‐like materials, we …

A Peptide-Based Oscillator

D Dev, N Wagner, B Pramanik, B Sharma… - Journal of the …, 2023 - ACS Publications
Living organisms are replete with rhythmic and oscillatory behavior at all levels, to the extent
that oscillations have been termed as a defining attribute of life. Recent studies of synthetic …

Antiviral activity of peptide-based assemblies

T Hu, O Agazani, S Nir, M Cohen, S Pan… - ACS Applied Materials …, 2021 - ACS Publications
The COVID-19 pandemic highlighted the importance of developing surfaces and coatings
with antiviral activity. Here, we present, for the first time, peptide-based assemblies that can …

Temporal Self-Regulation of Mechanical Properties via Catalytic Amyloid Polymers of a Short Peptide

S Bal, C Ghosh, P Parvin, D Das - Nano Letters, 2023 - ACS Publications
We report a short peptide that accessed dynamic catalytic polymers to demonstrate four-
stage (sol–gel–weak gel–strong gel) temporal self-regulation of its mechanical properties …

Reversible photoswitchable inhibitors generate ultrasensitivity in out-of-equilibrium enzymatic reactions

M Teders, AA Pogodaev, G Bojanov… - Journal of the American …, 2021 - ACS Publications
Ultrasensitivity is a ubiquitous emergent property of biochemical reaction networks. The
design and construction of synthetic reaction networks exhibiting ultrasensitivity has been …

Fluorescent Microswimmers Based on Cross‐β Amyloid Nanotubes and Divergent Cascade Networks

A Chatterjee, S Ghosh, C Ghosh… - Angewandte Chemie …, 2022 - Wiley Online Library
Shaped through millions of years of evolution, the spatial localization of multiple enzymes in
living cells employs extensive cascade reactions to enable highly coordinated multimodal …

[HTML][HTML] Autonomic self-regulating systems based on polyelectrolyte microcapsules and microgel particles

H Zhou, R Cheng, M Quarrell, D Shchukin - Journal of Colloid and Interface …, 2023 - Elsevier
Biological systems possess unique non-equilibrium functions, maintaining tight
manipulation of their surroundings through inter-communication of multiple components and …